Shellfish contamination by norovirus : strain selection based on ligand expression?
| Type | Article | ||||||||||||
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| Date | 2013 | ||||||||||||
| Language | English | ||||||||||||
| Author(s) | Le Guyader Soizick1, Atmar Robert2, Maalouf Haifa1, Le Pendu Jacques3 | ||||||||||||
| Affiliation(s) | 1 : IFREMER, BP 21105, 44311 Nantes cedex 03, France 2 : Baylor College of Medicine, 1 Baylor Plaza, MS BCM 280, Houston, TX 77030, USA 3 : INSERM U892, CNRS, 6299；Institut de Recherche Thérapeutique de l'Université de Nantes, 8 quai Moncousu, BP 70721, 44007 Nante cedex 1, France. |
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| Source | Rinsho to uirusu. Clinical virology (0303-8092) (Japanese Society of Clinical Virology), 2013 , Vol. 41 , N. 1 , P. 3-18 | ||||||||||||
| Keyword(s) | Shellfish, Noroviruses, Oyster contamination, Pathogen | ||||||||||||
| Abstract | Shellfish can be a vector for human pathogens. Despite regulation based on enteric bacteria, shellfish are still implicated in viral outbreaks. Oysters are the most common shellfish associated with outbreaks, and noroviruses, which cause acute gastroenteritis, are the most frequently identified pathogen in these outbreaks. Analysis of shellfish-related outbreak data worldwide shows an unexpected high proportion of NoV GI strains. Recent studies performed in vitro, in vivo and in the environment indicate that oysters are not just a passive filter, but can selectively accumulate norovirus strains based on virus carbohydrate ligands shared with humans. These observations may help explain the GI/GII bias observed in shellfish-related outbreaks compared to other outbreaks | ||||||||||||
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