Fitness landscapes support the dominance theory of post-zygotic isolation in the mussels Mytilus edulis and M. galloprovincialis
Type | Article | ||||||||
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Date | 2006-05 | ||||||||
Language | English | ||||||||
Author(s) | Bierne Nicolas1, Bonhomme Francois1, Boudry Pierre2, Szulkin M1, David Pierre3 | ||||||||
Affiliation(s) | 1 : UMII, CNRS, UMR 5171,Stn Mediterraneenne Environm Littoral, IFREMER,Lab Genome Populat Interact Adaptat, F-34200 Sete, France. 2 : CNRS, CEFE, F-34293 Montpellier, France. 3 : IFREMER, Lab Genet & Pathol, F-17390 La Tremblade, France. |
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Source | Proceedings of the Royal society of London (B) (Biological sciences) (0962-8452) (Royal Society of London), 2006-05 , Vol. 273 , N. 1591 , P. 1253-1260 | ||||||||
DOI | 10.1098/rspb.2005.3440 | ||||||||
WOS© Times Cited | 51 | ||||||||
Keyword(s) | Mytilus, Dobzhansky Muller incopatibilities, Post zygotic isolation, Negative epistasis, Hybrid breakdown, Hybrid zone | ||||||||
Abstract | We studied the genetic basis of post-zygotic isolation in the marine mussels Mytilus edulis and Mytilus galloprovincialis. Evidence was obtained for a high number of recessive Dobzhansky-Muller substitutions in the genome of these two mussel taxa. We analysed the segregation of unlinked diagnostic markers in the progeny of two backcrosses and an F-2 cross, 36 h and 200 days after fertilization. Directional selection favouring M. galloprovincialis genotypes was observed in both kinds of cross. In the F-2, epistatic interactions between each pair of chromosome fragments mapped by the markers were identified in addition. Our results imply that homozygous-homozygous interactions are required for breakdown of coadaptation, in accordance with the dominance theory of post-zygotic isolation. Endogenous post-zygotic selection distributed over many loci throughout the genome provides the missing factor explaining the astonishing persistence and strength of barriers to neutral introgression in such a dispersive taxon as Mytilus. | ||||||||
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