Fitness landscapes support the dominance theory of post-zygotic isolation in the mussels Mytilus edulis and M. galloprovincialis

Type Article
Date 2006-05
Language English
Author(s) Bierne Nicolas1, Bonhomme Francois1, Boudry PierreORCID2, Szulkin M1, David Pierre3
Affiliation(s) 1 : UMII, CNRS, UMR 5171,Stn Mediterraneenne Environm Littoral, IFREMER,Lab Genome Populat Interact Adaptat, F-34200 Sete, France.
2 : CNRS, CEFE, F-34293 Montpellier, France.
3 : IFREMER, Lab Genet & Pathol, F-17390 La Tremblade, France.
Source Proceedings of the Royal society of London (B) (Biological sciences) (0962-8452) (Royal Society of London), 2006-05 , Vol. 273 , N. 1591 , P. 1253-1260
DOI 10.1098/rspb.2005.3440
WOS© Times Cited 49
Keyword(s) Mytilus, Dobzhansky Muller incopatibilities, Post zygotic isolation, Negative epistasis, Hybrid breakdown, Hybrid zone
Abstract We studied the genetic basis of post-zygotic isolation in the marine mussels Mytilus edulis and Mytilus galloprovincialis. Evidence was obtained for a high number of recessive Dobzhansky-Muller substitutions in the genome of these two mussel taxa. We analysed the segregation of unlinked diagnostic markers in the progeny of two backcrosses and an F-2 cross, 36 h and 200 days after fertilization. Directional selection favouring M. galloprovincialis genotypes was observed in both kinds of cross. In the F-2, epistatic interactions between each pair of chromosome fragments mapped by the markers were identified in addition. Our results imply that homozygous-homozygous interactions are required for breakdown of coadaptation, in accordance with the dominance theory of post-zygotic isolation. Endogenous post-zygotic selection distributed over many loci throughout the genome provides the missing factor explaining the astonishing persistence and strength of barriers to neutral introgression in such a dispersive taxon as Mytilus.
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Bierne Nicolas, Bonhomme Francois, Boudry Pierre, Szulkin M, David Pierre (2006). Fitness landscapes support the dominance theory of post-zygotic isolation in the mussels Mytilus edulis and M. galloprovincialis. Proceedings of the Royal society of London (B) (Biological sciences), 273(1591), 1253-1260. Publisher's official version : https://doi.org/10.1098/rspb.2005.3440 , Open Access version : https://archimer.ifremer.fr/doc/00000/1350/