A large multi-pathogen waterborne community outbreak linked to faecal contamination of a groundwater system, France, 2000

Type Article
Date 2006-06
Language English
Author(s) Gallay A1, De Valk H1, Cournot M2, Ladeuil B4, Hemery C2, Castor C1, Bon F3, Megraud F5, Le Cann Pierre6, Desenclos Jc1
Affiliation(s) 1 : Inst Veille Sanitaire, F-94415 St Maurice, France.
2 : Cellule Interreg Epidemiol Intervent Sud Ouest, Toulouse, France.
3 : CHU Dijon, Ctr Natl Reference Virus Enter, Dijon, France.
4 : Direct Dept Agr Foret Lot, Cahors, France.
5 : CHU Pellegrin Bordeaux, Ctr Natl Reference Campylobacters & Helicobacters, Bordeaux, France.
6 : IFREMER, F-44311 Nantes 3, France.
Source Clinical Microbiology and Infection (1198-743X) (Blackwell science), 2006-06 , Vol. 12 , N. 6 , P. 561-570
DOI 10.1111/j.1469-0691.2006.01441.x
WOS© Times Cited 93
Keyword(s) Waterborne outbreak, Rotavirus, Norovirus, Gastroenteritis, Epidemiology, Campylobacter coli
Abstract A large waterborne outbreak of infection that occurred during August 2000 in a local community in France was investigated initially via a rapid survey of visits to local physicians. A retrospective cohort study was then conducted on a random cluster sample of residents. Of 709 residents interviewed, 202 (28.5%) were definite cases (at least three liquid stools/day or vomiting) and 62 (8.7%) were probable cases (less than three liquid stools/day or abdominal pain). Those who had drunk tap water had a three-fold increased risk for illness (95% CI 2.4-4.0). The risk increased with the amount of water consumed (chi-square trend: p < 0.0001). Bacteriological analyses of stools were performed for 35 patients and virological analyses for 24 patients. Campylobacter coli, group A rotavirus and norovirus were detected in 31.5%, 71.0% and 21% of samples, respectively. An extensive environmental investigation concluded that a groundwater source to this community had probably been contaminated by agricultural run-off, and a failure in the chlorination system was identified. This is the first documented waterborne outbreak of infection involving human C. coli infections. A better understanding of the factors influencing campylobacter transmission between hosts is required.
Full Text
File Pages Size Access
publication-1696.pdf 16 138 KB Open access
Top of the page

How to cite 

Gallay A, De Valk H, Cournot M, Ladeuil B, Hemery C, Castor C, Bon F, Megraud F, Le Cann Pierre, Desenclos Jc (2006). A large multi-pathogen waterborne community outbreak linked to faecal contamination of a groundwater system, France, 2000. Clinical Microbiology and Infection, 12(6), 561-570. Publisher's official version : https://doi.org/10.1111/j.1469-0691.2006.01441.x , Open Access version : https://archimer.ifremer.fr/doc/00000/1696/