FN Archimer Export Format
PT J
TI Expression of immune-related genes in the oyster Crassostrea gigas during ontogenesis
BT 
AF TIRAPE, Ana
   BACQUE, Coralie
   BRIZARD, Raphael
   VANDENBULCKE, Franck
   BOULO, Viviane
AS 1:1;2:1;3:2;4:3;5:2;
FF 1:;2:;3:PDG-DOP-DCN-AGSAE-LGP;4:;5:PDG-DOP-DCM-BOME-LALR;
C1 Univ Montpellier 2, UMR5171, IFREMER, CNRS, F-34095 Montpellier 5, France.
   IFREMER, Lab Genet & Pathol, F-17390 La Tremblade, France.
   Univ Lille 1, Lab Ecol Numer & Ecotoxicol, EA 3570, F-59655 Villeneuve Dascq, France.
C2 UNIV MONTPELLIER, FRANCE
   IFREMER, FRANCE
   UNIV LILLE, FRANCE
SI MONTPELLIER
   LA TREMBLADE
SE PDG-DOP-DCM-BOME-LALR-GPIA
   PDG-DOP-DCN-AGSAE-LGP
   PDG-DOP-DCM-BOME-LALR
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 3.155
TC 62
UR https://archimer.ifremer.fr/doc/2007/publication-2612.pdf
LA English
DT Article
DE ;Rel/NF kappa B pathway;Cell proliferation;Hematopoiesis;Mollusk immunity;Hemocytes;Bivalve mollusk
AB The work presented here reports the expression of immune-related genes during ontogenesis in the oyster Crassostrea gigar. Expression patterns of 18 selected genes showed that RNAs detected in oocytes and 2-4 cell embryos are of maternal origin and that gene transcription starts early after fertilization. The expression patterns of 4 genes (Cg-timp, Cg-tal, Cg-EcSOD and Drac3) suggested that hemocytes appear in the gastrula-trochophore stages. The localization of Cg-tal expression suggested that hematopoietic cells were derived from vessels and/or artery endothelia cells. Moreover, a bacterial challenge affected the level of expression of genes. Indeed, a change in expression levels was observed for Cg-LBP/BPI, Cg-timp, Drac3 and Cg-MyD88 genes in larval stages upon exposure to non-pathogenic bacteria. In early juveniles, a modulation was also observed for Cg-LBP/BPI, Cg-timp, Cg-MyD88 and for Cg-tal, according to the concentration of bacteria. Altogether, the results showed that studying the appearance of immunocompetent cells through their ability to express immune-related genes is a tool to gain insight the ontogenesis of the oyster immune system. (C) 2007 Elsevier Ltd. All rights reserved.
PY 2007
PD JUN
SO Developmental & Comparative Immunology
SN 0145-305X
PU Elsevier
VL 31
IS 9
UT 000247553800001
BP 859
EP 873
DI 10.1016/j.dci.2007.01.005
ID 2612
ER

EF