Study of atrazine effects on Pacific oyster, Crassostrea gigas, haemocytes

Type Article
Date 2003
Language English
Author(s) Gagnaire Beatrice, Renault Tristan, Bouilly Karine, Lapegue SylvieORCID, Thomas-Guyon H
Affiliation(s) IFREMER La Tremblade, Lab Genet & Pathol, F-17390 Ronce Les Bains, La Tremblade, France.
Univ La Rochelle, LBEM, F-17042 La Rochelle, France.
Source Current Pharmaceutical Design (1381-6128) (Bentham Science Publ Ltd), 2003 , Vol. 9 , N. 2 , P. 193-199
WOS© Times Cited 27
Keyword(s) Crassostrea gigas, haemocytes, flow cytometry, atrazine, cellular activities, toxicity
Abstract Shellfish farming is an important economic activity around the world. This activity often takes place in areas subjected to various recurring pollutions. The recrudescent use of herbicides in agriculture including atrazine implies pollutant transfer towards aquatic environment in estuarine areas. Harmful effects of such substances on animals in marine environment, particularly on cultured bivalves, are poorly documented. Bivalve molluscs such as mussels and oysters have been postulated as ideal indicator organisms because of their way of life. They filter large volumes of seawater and may therefore accumulate and concentrate eontaJ.11inants within their tissues. Moreover, development of techniques allowing effect analysis of such compounds on bivalve biology may lead to the development of diagnosis tools adapted to analyze pollutant transfer towards estuarine areas. In this context, influence of atrazine on defence mechanisms was analyzed in Pacific oysters, Crassostrea gigas. Atrazine was tested in vitro and in vivo on oyster haemocytes, and its effects were analyzed by flow cytometry. Haemocyte viability, cell cycle and cellular activities were monitored. Atrazine induced no significant effect in oyster under tested conditions except for peroxidase activity.
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Gagnaire Beatrice, Renault Tristan, Bouilly Karine, Lapegue Sylvie, Thomas-Guyon H (2003). Study of atrazine effects on Pacific oyster, Crassostrea gigas, haemocytes. Current Pharmaceutical Design, 9(2), 193-199. Open Access version :