TY - JOUR T1 - Determination of peptaibol trace amounts in marine sediments by liquid chromatography/electrospray ionization-ion trap-mass spectrometry A1 - Poirier,Laurence A1 - Amiard,Jean-Claude A1 - Mondeguer,Florence A1 - Quiniou,Francoise A1 - Ruiz,Nicolas A1 - Pouchus,Yves Francois A1 - Montagu,Monique AD - Univ Nantes, Nantes Atlantique Univ, SMAB EA2160, Fac Pharm, F-44000 Nantes, France. AD - IFREMER, DEL PN, Ctr Nantes, F-44311 Nantes 3, France. AD - IFREMER, Ctr Brest, BE EX, F-29280 Plouzane, France. UR - https://archimer.ifremer.fr/doc/00000/2990/ DO - 10.1016/j.chroma.2007.04.006 KW - Matched calibration KW - Matrix KW - Electrospray ionization ion trap mass spectrometry ESI IT MS KW - Marine fungal contamination KW - Trichoderma sp. KW - Fungal peptide metabolites N2 - Extraction followed by reverse phase liquid chromatography (LC)/electrospray ionization-ion trap-mass spectrometry (ESI-IT-MS) analysis has been successfully developed for the determination of peptaibols, fungal toxic metabolites, in marine sediments. Spiking experiments showed that the mean recovery of target compounds exceeded 85% at a spiking level of 10 ng/g of sediment (wet weight). Detection and quantification limits were 250 and 830 pg/g of sediment, respectively. The method developed constituted the first sensitive assay for quantification of peptaibol trace amounts in a natural environment. A concentration of 5 ng/g in sediment samples collected from Fier d'Ars was found. Y1 - 2007/08 PB - Elsevier JF - Journal of Chromatography A SN - 0021-9673 VL - 1160 IS - 1-2 SP - 106 EP - 113 ID - 2990 ER -