Producing recombinant commercial proteins

Other titles Les microalgues : usines cellulaires productrices de molécules commerciales recombinantes
Type Article
Date 2008-04
Language English
Author(s) Cadoret Jean-Paul1, Bardor M2, Lerouge P2, Cabigliera M, Henriquez Vitalia3, Carlier Aude1
Affiliation(s) 1 : Ctr Nantes, IFREMER, Lab PBA, F-44311 Nantes 03, France.
2 : Univ Rouen, CNRS, UMR 6037, IFRMP 23,Fac Sci, F-76821 Mont St Aignan, France.
3 : Pontificia Univ Catolica Chile, Inst Biol, Lab Genet & Inmunol Mol, Valparaiso, Chile.
Source MS Médecine Sciences (0767-0974) (EDK), 2008-04 , Vol. 24 , N. 4 , P. 375-382
WOS© Times Cited 20
Mot-Clé(s) génétique, recombinant, algues, pharmaceutique, transfert de gène, Biotechnologie
Keyword(s) genetics, recombinant, algae, pharmaceuticals, gene transfer, Biotechnology
Abstract Extraction of natural substances and chemical synthesis are the main sources of pharmaceutical molecules. When possible, one may transfer the gene of the molecule in living cells creating individual factories producing on demand and in a safe way the requested molecule. Today, bacteria, yeast, mammalian cells and plants constitute the main plate-forms for various commercial products. Microalgae present numerous advantages and could offer a powerful tool for the production of commercial molecules in a near future.
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Cadoret Jean-Paul, Bardor M, Lerouge P, Cabigliera M, Henriquez Vitalia, Carlier Aude (2008). Producing recombinant commercial proteins. MS Médecine Sciences, 24(4), 375-382. Open Access version : https://archimer.ifremer.fr/doc/00000/4045/