FN Archimer Export Format
PT J
TI Rapid accumulation of an interleukin 17 homolog transcript in Crassostrea gigas hemocytes following bacterial exposure
BT 
AF ROBERTS, S
   GUEGUEN, Yannick
   DE LORGERIL, Julien
   GOETZ, F
AS 1:2;2:3;3:3;4:1;
FF 1:;2:PDG-DOP-DCM-BOME-LALR;3:PDG-DOP-DCM-BOME-LALR;4:;
C1 Univ Wisconsin, Great Lakes WATER Inst, Milwaukee, WI 53204 USA.
   Univ Washington, Sch Aquat & Fisheries Sci, Seattle, WA 98105 USA.
   IFREMER, Univ Montpellier 2, CNRS, UMR Ecosyst Lagunaires 5119, Montpellier 5, France.
C2 UNIV WISCONSIN, USA
   UNIV WASHINGTON, USA
   IFREMER, FRANCE
SI MONTPELLIER
SE PDG-DOP-DCM-BOME-LALR
IN WOS Ifremer jusqu'en 2018
   copubli-int-hors-europe
IF 2.833
TC 75
UR https://archimer.ifremer.fr/doc/2008/publication-4151.pdf
LA English
DT Article
DE ;Invertebrate innate immunity;Crassostrea gigas;Invertebrate cytokines;Hemocytes;Pacific oyster;Interleukin
AB Interleukin-17 (IL-17) gene models have been found in the sequenced genomes of Strongylocentrotus purpuratus and Caenorhabditis elegans. However, there have been no published reports on the empirical cloning and characterization of any interleukin cDNAs in invertebrates. From a Pacific oyster (Crossostrea gigas) hemocyte cDNA library, two clones were obtained that encoded a protein similar to vertebrate IL-17s. The putative oyster IL-17 homolog (CgIL-17) was 27% identical to rainbow trout IL-17D, 21% to human IL-17D and 24% to an IL-17D-like gene model obtained from the annotation of the sea urchin genome. IL-17s from the oyster, sea urchin, trout and human, contained conserved cysteine residues found in all forms of IL-17 in mammals. Injection of bacteria into C. gigas oysters produced a large and rapid elevation in CgIL-17 transcript abundance in hemocytes, suggesting that this is a very early response gene to pathogens that may be responsible for the stimulation of other immune genes in the oyster. (c) 2008 Elsevier Ltd. All rights reserved.
PY 2008
PD FEB
SO Developmental & Comparative Immunology
SN 0145-305X
PU Elsevier
VL 32
IS 9
UT 000256134900010
BP 1099
EP 1104
DI 10.1016/j.dci.2008.02.006
ID 4151
ER

EF