FN Archimer Export Format PT J TI A relationship between antimicrobial peptide gene expression and capacity of a selected shrimp line to survive a Vibrio infection BT AF DE LORGERIL, Julien GUEGUEN, Yannick GOARANT, Cyrille GOYARD, Emmanuel MUGNIER, Chantal FIEVET, Julie PIQUEMAL, D BACHERE, Evelyne AS 1:1,2;2:1;3:2;4:2;5:2;6:1;7:3;8:1; FF 1:PDG-DOP-DCM-BOME-LALR;2:PDG-DOP-DCOP-AQUAPOL-LBQP;3:PDG-DOP-DCOP-AQNC;4:PDG-DOP-DCOP-AQNC;5:PDG-DOP-DCOP-AQNC;6:PDG-DOP-DCM-BOME-LALR;7:;8:PDG-DOP-DCM-BOME; C1 Univ Montpellier 2, CNRS, IFREMER, UMR Ecosyst Lagunaires 5119, F-34095 Montpellier 5, France. IFREMER, Nouvelle Caledonie, F-98846 Noumea, France. Skuld Tech, F-34080 Montpellier, France. C2 UNIV MONTPELLIER, FRANCE IFREMER, FRANCE SKULD TECH, FRANCE SI MONTPELLIER TAHITI SAINT VINCENT BREST PALAVAS SE PDG-DOP-DCM-BOME-LALR PDG-DOP-DCOP-AQUAPOL-LBQP PDG-DOP-DCOP-AQNC PDG-DOP-DCM-BOME IN WOS Ifremer jusqu'en 2018 copubli-france copubli-univ-france IF 3.555 TC 44 UR https://archimer.ifremer.fr/doc/2008/publication-4524.pdf LA English DT Article DE ;Real time PCR;Cysteine rich peptide;Crustin;Anti LPS factor;Lysozyme;Penaeidins;Immune response;Vibrio penaeicida;Penaeid;Decapoda;Crustacean AB Understanding of antimicrobial defence mechanisms of penaeid shrimp should help in the design of efficient strategies for the management and disease control in aquaculture. In this study, we have specifically analysed the expression in circulating hemocytes of antimicrobial peptides (AMPs) encoding genes, such as PEN2 and PEN3, ALF, crustin, lysozyme and a putative cysteine-rich peptide. We evidenced a relationship between the level of expression of some AMPs and the successful response of the shrimp, Litopenaeus stylirostris, to circumvent a pathogenic Vibrio penaeicida infection. Additionally, significant differences in some AMP transcript amounts are evidenced between control, non-selected shrimp line and the third generation breeding of shrimp selected for their survival to natural V. penaeicida infections. On the basis of these results, it will now be of great interest to determine if these AMPs are directly involved in the resistance of shrimp to infection or if they only reflect other acquired defence mechanisms which can confer a resistance. (C) 2008 Elsevier Ltd. All rights reserved. PY 2008 PD JUN SO Molecular Immunology SN 0161-5890 PU Elsevier VL 45 IS 12 UT 000257575500014 BP 3438 EP 3445 DI 10.1016/j.molimm.2008.04.002 ID 4524 ER EF