FN Archimer Export Format
PT J
TI Brown muscle disease (BMD), an emergent pathology affecting Manila clam Ruditapes philippinarum in Arcachon Bay (SW France)
BT 
AF DANG, C
   DE MONTAUDOUIN, X
   GONZALEZ, P
   MESMER DULDONS, N
   CAILL-MILLY, Nathalie
AS 1:1;2:1;3:1;4:1;5:2;
FF 1:;2:;3:;4:;5:PDG-DOP-DCN-HGS-LRHAQ;
C1 Univ Bordeaux 1, CNRS, EPOC,Stn Marine Arcachon, UMR 5805, F-33120 Arcachon, France.
   IFREMER, Lab Ressources Halieut Aquitaine, F-64600 Anglet, France.
C2 UNIV BORDEAUX, FRANCE
   IFREMER, FRANCE
SI ANGLET
SE PDG-DOP-DCN-HGS-LRHAQ
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 1.586
TC 22
UR https://archimer.ifremer.fr/doc/2008/publication-4556.pdf
LA English
DT Article
CR EVALUATION STOCK PALOURDES BASSIN D'ARCACHON
DE ;Light microscopy;Pathology;Adductor muscle;Ruditapes philippinarum;Clam;Brown muscle disease
AB We describe an emerging pathology, brown muscle disease (BMD), which specifically affects the Manila clam Ruditapes philippinarum in Arcachon Bay (France). BMD induces a transformation of the posterior adductor muscle, which becomes infused by conchiolin and calcified, reducing the ability of clams to bury. The disease affects both types of muscular tissue, with striated muscle becoming affected to a higher degree than smooth muscle. Two indices were created to quantify the symptoms: the Muscle Print Index, used for empty and live shells, and the Final Disease Index, utilized for live clams only. Histological sections were made and observed under light microscopy to examine the muscular damage and to investigate a causal agent. Sections revealed an important inflammatory response with a large invasion of hemocytes into tissues and a heavy necrosis of muscular fibers. Additionally, molecular biology analyses were carried out to search for bacteria and protozoan agents using generic primers. In both histological and molecular assays, bacteria and protozoans were discounted. We monitored 4 sites scattered around the bay over 2 yr. The mean prevalence was < 12% without seasonal variation in 3 sites against 30% and a winter peak in 1 site. The latter site was accurately surveyed and revealed that clams at the sediment surface (abnormal position) were affected 3 times more frequently than buried clams (normal position).
PY 2008
PD AUG
SO Diseases of aquatic organisms
SN 0177-5103
PU Inter-Research
VL 80
IS 3
UT 000258940800006
BP 219
EP 228
DI 10.3354/dao01941
ID 4556
ER

EF