FN Archimer Export Format PT J TI High levels of vegetable oils in plant protein-rich diets fed to gilthead sea bream (Sparus aurata L.): growth performance, muscle fatty acid profiles and histological alterations of target tissues BT AF BENEDITO PALOS, L NAVARRO, J SITJA BOBADILLA, A BELL, J KAUSHIK, Sadasivam PEREZ SANCHEZ, J AS 1:1;2:1;3:1;4:2;5:3,4;6:1; FF 1:;2:;3:;4:;5:;6:; C1 Inst Aquaculture Torre Sal CSIC, Dept Biol Culture & Pathol Marine Species, Ribera De Cabanes 12595, Castellon, Spain. Univ Stirling, Inst Aquaculture, Stirling FK9 4LA, Scotland. Univ Bordeaux 1, UMR Nutr Aquaculture & Genom, Unite Mixte INRA, IFREMER, F-64310 St Pee Sur Nivelle, France. C2 INST AQUACULTURE TORRE SAL CSIC, SPAIN UNIV STIRLING, UK INRA, FRANCE IFREMER, FRANCE SI ST PEE SUR NIVELLE SE PDG-DOP-DCB-PFOM-ARN IN WOS Ifremer jusqu'en 2018 copubli-france copubli-p187 copubli-europe copubli-univ-france IF 2.764 TC 142 UR https://archimer.ifremer.fr/doc/2008/publication-4780.pdf LA English DT Article DE ;Lipoid liver disease;Soya lecithin;Phospholipids;Essential fatty acids AB The feasibility of fish oil (FO) replacement by vegetable oils (VO) was investigated in gilthead sea bream (Sparus aurata L.) in a growth trial conducted for the duration of 8 months. Four isolipidic and isoproteic diets rich in plant proteins were Supplemented with L-lysine (0-55%) and soya lecithin (1%). Added oil was either FO (control) or a blend of VO, replacing 33% (33VO diet), 66% (66VO diet) and 100% (VO diet) of FO. No detrimental effects on growth performance were found with the partial FO replacement, but feed intake and growth rates were reduced by about 10% in fish fed the VO diet. The replacement strategy did not damage the intestinal epithelium, and massive accumulation of lipid droplets was not found within enterocytes. All fish showed fatty livers, but signs of lipoid liver disease were only found in fish fed the VO diet. Muscle fatty acid profiles of total lipids reflected the diet composition with a selective incorporation of unsaturated fatty acids it) polar lipids. The robustness of the phospholipid fatty acid profile when essential fatty acid requirements were theoretically covered by the diet was evidenced by multivariate principal components analysis in fish fed control. 33VO and 66VO diets. PY 2008 PD NOV SO British Journal of Nutrition SN 0007-1145 PU Cambridge Univertsity Press VL 100 IS 5 UT 000260465300010 BP 992 EP 1003 DI 10.1017/S0007114508966071 ID 4780 ER EF