FN Archimer Export Format
PT J
TI Persistence of atrazine impact on aneuploidy in Pacific oysters, Crassostrea gigas
BT 
AF BOUILLY, Karine
   MCCOMBIE, Helen
   LEITAO, Alexandra
   LAPEGUE, Sylvie
AS 1:;2:;3:;4:;
FF 1:PDG-DRV-RA-LGP;2:PDG-DRV-RA-LGP;3:;4:PDG-DRV-RA-LGP;
C1 IFREMER, Lab Genet & Pathol, F-17390 La Tremblade, France.
C2 IFREMER, FRANCE
SI LA TREMBLADE
SE PDG-DRV-RA-LGP
IN WOS Ifremer jusqu'en 2018
IF 1.772
TC 18
UR https://archimer.ifremer.fr/doc/2004/publication-580.pdf
LA English
DT Article
DE ;Aneuploidy;Crassostrea gigas;Atrazine;Toxicity;Pollutant persistence
AB Widespread use of the herbicide atrazine has incited much research on its toxicity in aquatic systems, where it is routinely detected due to runoff from cultivated fields. Moreover, the determination of the genotoxic effect of such pollutants in the marine environment has become a major requirement for ecosystem protection. In the Pacific oyster, Crassostrea gigas, hypodiploid aneuploid cells have regularly been reported. There is a negative correlation between this phenomenon and growth, as well as evidence for a genetic basis. A positive relationship between atrazine and aneuploidy has previously been demonstrated in C. gigas adults and juveniles. To evaluate the persistence of this impact, our study examined the offspring of the same adult population previously treated with different atrazine doses (10 mug 1(-1), representing a peak value found in a polluted environment and 100 mug 1(-1)), and a seawater control. We observed that these offspring exhibited significantly higher aneuploidy levels when their parents had been exposed to atrazine (14.9-16.9% in comparison with the control where the levels ranged from 11.4% to 12.8%). In addition, the present study examined the aneuploidy level of a sample of juveniles, previously exposed for 3.5 months to the same doses of atrazine, then transferred to non-polluted conditions for an additional period of 2.5 months; this aneuploidy level remained significantly different between the treatments applied. These results demonstrate the persistence of an atrazine impact on Pacific oyster aneuploidy in time, within and between generations, indicating that this widely used compound may represent an important factor causing at least medium-term damage to genetic material.
PY 2004
PD SEP
SO Marine Biology
SN 0025-3162
PU Springer
VL 145
IS 4
UT 000224527600007
BP 699
EP 705
DI 10.1007/s00227-004-1369-8
ID 580
ER

EF