FN Archimer Export Format PT J TI Investigation of the matrix effects on a HPLC-ESI-MS/MS method and application for monitoring triazine, phenylurea and chloroacetanilide concentrations in fresh and estuarine waters BT AF MAZZELLA, N. DELMAS, F. DELEST, B. MECHIN, B. MADIGOU, C. ALLENOU, Jean-Pierre GABELLEC, Raoul CAQUET, Th. AS 1:1;2:1;3:1;4:1;5:1;6:2,3;7:2,3;8:4; FF 1:;2:;3:;4:;5:;6:PDG-DOP-LER-LERMPL;7:PDG-DOP-LER-LERMPL;8:; C1 UR REBX, Cemagref, F-33612 Cestas, France. Inst Francais Rech Exploitat Mer, Lab Cotier Morbihan Pays Loire, Nantes, France. Inst Francais Rech Exploitat Mer, Lab Cotier Morbihan Pays Loire, La Trinite Sur Mer, France. INRA, Equipe Ecotoxicol & Qualite Milieux Aquat, F-35042 Rennes, France. C2 CEMAGREF, FRANCE IFREMER, FRANCE IFREMER, FRANCE INRA, FRANCE SI LA TRINITE SE PDG-DOP-LER-LERMPL IN WOS Ifremer jusqu'en 2018 copubli-france copubli-p187 IF 2.225 TC 34 UR https://archimer.ifremer.fr/doc/2009/publication-6092.pdf LA English DT Article DE ;river estuarine interface;natural water quality;herbicides;matrix effects;multiresidue method;HPLC ESI MS/MS AB In this work, the effects of matrix interferences on the analytical performance of a new multiresidue method based on off-line solid phase extraction followed by reversed-phase liquid chromatographic separation and electrospray triple quadrupole mass spectrometric detection were investigated. This technique allows the simultaneous determination of 30 triazines, phenylureas and chloroacetanilides, extracted from freshwaters, in 40 minutes. Quantifications were performed with the use of appropriate internal standards (i.e. atrazine D5, diuron D6 and metolachlor D6). The limits of quantification were from 1 to 32 ng L-1 for the triazines, from 5 to 59 ng L-1 for the phenylureas and from 13 to 54 ng L-1 for the chloroacetanilides. The matrix effects were studied by spiking various waters (i.e. tap, river, pond and sea waters) with the chemicals of interest. The results showed that the samples with the highest conductivity (i.e. seawater) and the most abundant dissolved organic matter content (i.e. pond water) exhibited important matrix effects with signal suppressions and high imprecision, respectively. These matrix effects were strongly minimized by performing appropriate internal standardizations. Afterward, this analytical method was applied for analyzing environmental samples from either river or estuarine waters and for monitoring herbicide input in a freshwater-seawater interface. PY 2009 SO Journal of Environmental Monitoring SN 1464-0325 PU Royal Society of Chemistry VL 11 IS 1 UT 000262372000013 BP 108 EP 115 DI 10.1039/b805160g ID 6092 ER EF