FN Archimer Export Format
PT J
TI What is the heritable component of spinal deformities in the European sea bass (Dicentrarchus labrax)?
BT 
AF BARDON, Agnes
   VANDEPUTTE, Marc
   DUPONT-NIVET, Mathilde
   CHAVANNE, Herve
   HAFFRAY, Pierrick
   VERGNET, Alain
   CHATAIN, Beatrice
AS 1:2;2:1,2;3:1;4:3;5:4;6:2;7:2;
FF 1:PDG-DOP-DCM-BOME-LALR;2:;3:;4:;5:;6:PDG-DOP-DCM-BOME-LALR;7:PDG-DOP-DCM-BOME-LALR;
C1 INRA, UMR Genet Anim & Biol Integrat 1313, F-78350 Jouy En Josas, France.
   IFREMER, F-34250 Palavas Les Flots, France.
   Panitt Pugliese, Torre Canne Di Fasano, Italy.
   Sysaaf, Sect Aquacole, Stn SCRIBE, F-35042 Rennes, France.
C2 INRA, FRANCE
   IFREMER, FRANCE
   PANITT PUGLIESE, ITALY
   SYSAAF, FRANCE
SI PALAVAS
SE PDG-DOP-DCM-BOME-LALR
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-p187
   copubli-europe
IF 1.925
TC 39
UR https://archimer.ifremer.fr/doc/2009/publication-6768.pdf
LA English
DT Article
DE ;Genetic correlations;Heritability;Growth;Deformities;Dicentrarchus labrax;European sea bass
AB Malformations in farmed fish are a prime research topic as it has a major impact on fish welfare and on the economical value of the product. In this study, the genetic component of spine deformities was estimated in European sea bass, a major species of Mediterranean aquaculture, with the use of a posteriori reconstruction of pedigree with microsatellites. Our population exhibited a very high malformation rate (81%),probably due to intense swimming of fish during pre-growing The heritability of global spine deformities was evaluated to be 0.21 +/- 0.04 on the underlying scale (033 +/- 0.06 for lordosis, 0.13 +/- 0.04 for scoliosis). Deformities scored by an internal or external examination turned out to be genetically the same trait (genetic correlations>0.9), although phenotypic correlations were moderate to high (0.45 +/- 0.04 to 0.92 +/- 0.01) due to difficulties in scoring the less severe deformities. Along time (from 100 to 800 g mean weight), lordosis had a constant heritability, with very high genetic correlations between stages (>0.9). its incidence increased from 39 to 53% indicating that the malformation was probably present from the beginning of the rearing period but that its expression increased overtime. A positive linkage between spine deformities and growth rate was demonstrated both by the higher early weight of affected fish and by the positive genetic correlation between weight and malformation (from 0.21 +/- 0.15 to 0.40 +/- 0.14), although deformities have a negative phenotypic impact on growth. However, heritabilities of malformation traits calculated here are only estimates that may indirectly describe the sensitivity of fish to the particular pre-growing environment as a function of different body weight genotypes. A quantification of realised heritability would therefore be necessary before concluding on the existence of a genetic basis for spinal malformations such as lordosis and scoliosis. Nevertheless and by precaution, selection for fast growth rate needs careful monitoring of deformities, and selection against malformations may counteract impacts of selection for fast growth. (c) 2009 Elsevier B.V. All rights reserved.
PY 2009
PD SEP
SO Aquaculture
SN 0044-8486
PU Elsevier
VL 294
IS 3-4
UT 000269290500007
BP 194
EP 201
DI 10.1016/j.aquaculture.2009.06.018
ID 6768
ER

EF