Effects of rapeseed meal-glucosinolates on thyroid metabolism and feed utilization in rainbow trout

Type Article
Date 2001-12
Language English
Author(s) Burel Christine, Boujard Thierry, Kaushik Sadasivam, Boeuf Gilles, Mol K, Van Der Geyten S, Darras V, Kuhn E, Pradet Balade B, Querat B, Quinsac A, Krouti M, Ribaillier D
Affiliation(s) INRA, Stn Hydrobiol, Unite Mixte INRA IFREMER Nutr Poissons, F-64310 St Pee Sur Nivelle, France.
IFREMER, Stn Brest, Physiol Poissons Lab, F-29280 Plouzane, France.
Catholic Univ Louvain, Lab Comparat Endocrinol, B-3000 Louvain, Belgium.
CSIC, Ctr Nacl Biotecnol, E-28049 Madrid, Spain.
Museum Natl Hist Nat, Lab Physiol Gen & Comparee, F-75231 Paris, France.
Lab Anal CETIOM, F-45160 Ardon, France.
Source General and Comparative Endocrinology (0016-6480) (Elsevier), 2001-12 , Vol. 124 , N. 3 , P. 343-358
DOI 10.1006/gcen.2001.7723
WOS© Times Cited 57
Keyword(s) Rainbow trout, Iodine, TSH, Deiodinase activity, Thyroid function, Growth, Glucosinolates, Rapeseed
Abstract Two rapeseed meals (RM1 and RM2), containing glucosinolates at a concentration of 26 and 40 mumol/g, respectively, were incorporated at increasing levels (10, 20, and 30% for RM1 and 30 and 50% for RM2) in diets of juvenile rainbow trout. Disturbances in the thyroid axis appeared after 14 days of feeding (with a dietary incorporation level of 10%). The dietary supplementation with T-3 or iodine induced an increase in plasma T-3 levels, compared to that in fish fed the RM diets, and reduced the deleterious effect of RM on growth. When trout were reared in seawater, there was also a slight increase in thyroid hormone levels. TSH treatment had no effect on the thyroid hormone plasma levels. The incorporation of 30% of RM1, which induced a lower dietary content of toxic compounds than RM2, led to a rapid decrease of plasma T-4 and T-3 levels, but growth was affected only after 6 months of feeding. During these studies, the deiodinase activities responded in a complex manner to restore plasma and tissue levels of T-3.
Full Text
File Pages Size Access
publication-677.pdf 42 229 KB Open access
Top of the page

How to cite 

Burel Christine, Boujard Thierry, Kaushik Sadasivam, Boeuf Gilles, Mol K, Van Der Geyten S, Darras V, Kuhn E, Pradet Balade B, Querat B, Quinsac A, Krouti M, Ribaillier D (2001). Effects of rapeseed meal-glucosinolates on thyroid metabolism and feed utilization in rainbow trout. General and Comparative Endocrinology, 124(3), 343-358. Publisher's official version : https://doi.org/10.1006/gcen.2001.7723 , Open Access version : https://archimer.ifremer.fr/doc/00000/677/