Effects of rapeseed meal-glucosinolates on thyroid metabolism and feed utilization in rainbow trout
| Type | Article | ||||||||
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| Date | 2001-12 | ||||||||
| Language | English | ||||||||
| Author(s) | Burel Christine, Boujard Thierry, Kaushik Sadasivam, Boeuf Gilles, Mol K, Van Der Geyten S, Darras V, Kuhn E, Pradet Balade B, Querat B, Quinsac A, Krouti M, Ribaillier D | ||||||||
| Affiliation(s) | INRA, Stn Hydrobiol, Unite Mixte INRA IFREMER Nutr Poissons, F-64310 St Pee Sur Nivelle, France. IFREMER, Stn Brest, Physiol Poissons Lab, F-29280 Plouzane, France. Catholic Univ Louvain, Lab Comparat Endocrinol, B-3000 Louvain, Belgium. CSIC, Ctr Nacl Biotecnol, E-28049 Madrid, Spain. Museum Natl Hist Nat, Lab Physiol Gen & Comparee, F-75231 Paris, France. Lab Anal CETIOM, F-45160 Ardon, France. |
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| Source | General and Comparative Endocrinology (0016-6480) (Elsevier), 2001-12 , Vol. 124 , N. 3 , P. 343-358 | ||||||||
| DOI | 10.1006/gcen.2001.7723 | ||||||||
| WOS© Times Cited | 64 | ||||||||
| Keyword(s) | Rainbow trout, Iodine, TSH, Deiodinase activity, Thyroid function, Growth, Glucosinolates, Rapeseed | ||||||||
| Abstract | Two rapeseed meals (RM1 and RM2), containing glucosinolates at a concentration of 26 and 40 mumol/g, respectively, were incorporated at increasing levels (10, 20, and 30% for RM1 and 30 and 50% for RM2) in diets of juvenile rainbow trout. Disturbances in the thyroid axis appeared after 14 days of feeding (with a dietary incorporation level of 10%). The dietary supplementation with T-3 or iodine induced an increase in plasma T-3 levels, compared to that in fish fed the RM diets, and reduced the deleterious effect of RM on growth. When trout were reared in seawater, there was also a slight increase in thyroid hormone levels. TSH treatment had no effect on the thyroid hormone plasma levels. The incorporation of 30% of RM1, which induced a lower dietary content of toxic compounds than RM2, led to a rapid decrease of plasma T-4 and T-3 levels, but growth was affected only after 6 months of feeding. During these studies, the deiodinase activities responded in a complex manner to restore plasma and tissue levels of T-3. | ||||||||
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