FN Archimer Export Format
PT J
TI Shrimp Taura syndrome virus: genomic characterization and similarity with members of the genus Cricket paralysis-like viruses
BT 
AF MARI, Jocelyne
   POULOS, Bonnie
   LIGHTNER, Donald
   BONAMI, Jean-Robert
AS 1:;2:;3:;4:;
FF 1:;2:;3:;4:;
C1 Univ Arizona, Dept Vet Sci & Microbiol, Aquaculture Pathol Grp, Tucson, AZ 85721 USA.
   CNRS, IFREMER, UM2, UMR 5098,CC080, F-34095 Montpellier 5, France.
C2 UNIV ARIZONA, USA
   CNRS, FRANCE
SI MONTPELLIER
SE PDG-DRV-RA-DRIM
IN WOS Ifremer jusqu'en 2018
   copubli-int-hors-europe
IF 3.3
TC 118
UR https://archimer.ifremer.fr/doc/2002/publication-715.pdf
LA English
DT Article
DE ;Genomic characterization;Taura syndrome;Virus;Shrimp disease;Penaeidae
AB The single-stranded genomic RNA of Taura syndrome virus (TSV) is 10205 nucleotides in length, excluding the 3' poly(A) tail, and contains two large open reading frames (ORFs) that are separated by an intergenic region of 207 nucleotides. The ORFs are flanked by a 377 nucleotide 5' untranslated region (UTR) and a 226 nucleotide 3' UTR followed by a poly(A) tail. The predicted amino acid sequence of ORF1 revealed sequence motifs characteristic of a helicase, a protease and an RNA-dependent RNA polymerase, similar to the non-structural proteins of several plant and animal RNA viruses. In addition, a short amino acid sequence located in the N-terminal region of ORF1 presented a significant similarity with a baculovirus IAP repeat (BIR) domain of inhibitor of apoptosis proteins from double-stranded DNA viruses and from animals. The presence of this BIR-like sequence is the first reported in a single-stranded RNA virus, but its function is unknown. The N-terminal amino acid sequence of three TSV capsid proteins (55, 40 and 24 kDa) were mapped in ORF2, which is not in the same reading frame as ORF1 and possesses an AUG codon upstream of the structural genes. However, the intergenic region shows nucleotide sequence similarity with those of the genus Cricket paralysis-like viruses, suggesting a similar non-AUG-mediated translation mechanism. The structure of the TSV genome [5' UTR-non-structural proteins-intergenic UTR-structural proteins-3' UTR-poly(A) tail] is similar to those of small insect-infecting RNA viruses, which were recently regrouped into a new virus genus, Cricket paralysis-like viruses.
PY 2002
PD APR
SO Journal of General Virology
SN 0022-1317
PU Society for General Microbiology
VL 83
UT 000174503100023
BP 915
EP 926
ID 715
ER

EF