A di-O-dihydrogeranylgeranyl glycerol from Thermococus S 557, a novel ether lipid, and likely intermediate in the biosynthesis of diethers in Archaea
|Author(s)||Gonthier Isabelle, Rager Marie-Noëlle, Metzger Pierre, Guezennec Jean, Largeau Claude|
|Affiliation(s)||Ecole Natl Super Chim Paris, CNRS UMR 7573, F-75231 Paris 05, France.
Ecole Natl Super Chim, CNRS UMR 7576, Serv RMN, F-75231 Paris, France.
IFREMER, F-29280 Plouzane, France.
|Source||Tetrahedron Letters (0040-4039) (Elsevier), 2001-04 , Vol. 42 , N. 15 , P. 2795-2797|
|WOS© Times Cited||20|
|Keyword(s)||Mass spectrometry, NMR, Novel glycerol diether lipid, Thermococcus sp, Archaea|
|Abstract||The lipids of a deep-sea hydrothermal vent arch ae on, Thermococcus S 557, were isolated, purified and structurally determined. Based on acid methanolysis and spectroscopic studies, the polar lipids were shown to comprise diphytanyl glycerol and dibiphytanyl diglycerol, typical membrane lipids of Arch aea. From the neutral lipids, 2,3-di-O-dihydro-14,15-geranylgeranyl glycerol was isolated. This novel ether lipid is, very likely, a close intermediate in the biosynthesis of diphytanyl glycerol diether in Arch aea.|