FN Archimer Export Format PT J TI QTL for resistance to summer mortality and OsHV-1 load in the Pacific oyster (Crassostrea gigas) BT AF SAUVAGE, Christopher BOUDRY, Pierre DE KONING, D. -J. HALEY, C. S. HEURTEBISE, Serge LAPEGUE, Sylvie AS 1:1;2:2;3:3,4;4:3,4;5:1;6:1; FF 1:PDG-DOP-DCN-AGSAE-LGP;2:PDG-DOP-DCB-PFOM-PI;3:;4:;5:PDG-DOP-DCN-AGSAE-LGP;6:PDG-DOP-DCN-AGSAE-LGP; C1 IFREMER, Lab Genet & Pathol, F-17390 La Tremblade, France. IFREMER, UMR M100, Lab Physiol & Ecophysiol Mollusques Marins, F-29280 Plouzane, France. Roslin Inst, Div Genet & Genom, Roslin EH25 9PS, Midlothian, Scotland. Univ Edinburgh, Roslin Bioctr, R D SVS, Roslin EH25 9PS, Midlothian, Scotland. C2 IFREMER, FRANCE IFREMER, FRANCE ROSLIN INST, UK UNIV EDINBURGH, UK SI LA TREMBLADE BREST SE PDG-DOP-DCN-AGSAE-LGP PDG-DOP-DCB-PFOM-PI IN WOS Ifremer jusqu'en 2018 copubli-europe IF 2.203 TC 73 UR https://archimer.ifremer.fr/doc/00011/12241/9063.pdf LA English DT Article DE ;Crassostrea gigas;herpes virus;Pacific oyster;QTL mapping;summer mortality AB P>Summer mortality is a phenomenon severely affecting the aquaculture production of the Pacific oyster (Crassostrea gigas). Although its causal factors are complex, resistance to mortality has been described as a highly heritable trait, and several pathogens including the virus Ostreid Herpes virus type 1 (OsHV-1) have been associated with this phenomenon. A QTL analysis for survival of summer mortality and OsHV-1 load, estimated using real-time PCR, was performed using five F-2 full-sib families resulting from a divergent selection experiment for resistance to summer mortality. A consensus linkage map was built using 29 SNPs and 51 microsatellite markers. Five significant QTL were identified and assigned to linkage groups V, VI, VII and IX. Analysis of single full-sib families revealed differential QTL segregation between families. QTL for the two-recorded traits presented very similar locations, highlighting the interest of further study of their respective genetic controls. These QTL show substantial genetic variation in resistance to summer mortality, and present new opportunities for selection for resistance to OsHV-1. PY 2010 PD AUG SO Animal Genetics SN 0268-9146 PU Wiley-blackwell Publishing, Inc VL 41 IS 4 UT 000279717800006 BP 390 EP 399 DI 10.1111/j.1365-2052.2009.02018.x ID 12241 ER EF