FN Archimer Export Format
PT J
TI Transcriptomic response of the Pacific oyster Crassostrea gigas to hypoxia
BT 
AF SUSSARELLU, Rossana
   FABIOUX, Caroline
   LE MOULLAC, Gilles
   FLEURY, Elodie
   MORAGA, Dario
AS 1:1;2:1;3:2;4:3;5:1;
FF 1:;2:;3:PDG-DOP-DCOP-AQUAPOL-LDHP;4:PDG-DOP-DCOP-AQUAPOL;5:;
C1 Univ Bretagne Occidentale, CNRS, LEMAR, Lab Sci Environm Marin,IUEM,UMR 6539, F-29280 Plouzane, France.
   IFREMER, Lab Domesticat Huitre Perliere, Dept Lagon Environm Aquaculture Durable Polynesie, Ctr Pacifique, Taravao 98719, Fr Polynesia.
   Univ Caen Basse Normandie, IFREMER, Lab Physiol & Ecophysiol Mollusques Marins, Ctr Brest,UMR M100, F-29280 Plouzane, France.
C2 UBO, FRANCE
   IFREMER, FRANCE
   UNIV CAEN, FRANCE
SI TAHITI
SE PDG-DOP-DCOP-AQUAPOL-LDHP
   PDG-DOP-DCOP-AQUAPOL
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 0.841
TC 61
UR https://archimer.ifremer.fr/doc/00027/13799/11053.pdf
   https://archimer.ifremer.fr/doc/00027/13799/11055.pdf
   https://archimer.ifremer.fr/doc/00027/13799/11056.pdf
   https://archimer.ifremer.fr/doc/00027/13799/11057.pdf
LA English
DT Article
DE ;Mollusca;Hypoxia;cDNA microarray;Gene expression;Oxidative stress;Respiratory chain
AB Marine intertidal organisms commonly face hypoxic stress during low tide emersion; moreover, eutrophic conditions and sediment nearness could lead to hypoxic phenomena; it is indeed important to understand the molecular processes involved in the response to hypoxia. In this study the molecular response of the Pacific oyster Crassostrea gigas to prolonged hypoxia (2 mg O-2 L-1 for 20 d) was investigated under experimental conditions. A transcriptomic approach was employed using a cDNA microarray of 9058 C. gigas clones to highlight the genetic expression patterns of the Pacific oyster under hypoxic conditions. Lines of oysters resistant (R) and susceptible (S) to summer mortality were used in this study. ANOVA analysis was used to identify the genes involved in the response to hypoxia in comparison to normoxic conditions. The hypoxic response was maximal at day 20. The principal biological processes up-regulated by hypoxic stress were antioxidant defense and the respiratory chain compartment, suggesting oxidative stress caused by hypoxia or an anticipatory response for normoxic recovery. This is the first study employing microarrays to characterize the genetic markers and metabolic pathways responding to hypoxic stress in C gigas. (C) 2010 Elsevier B.V. All rights reserved.
PY 2010
PD SEP
SO Marine Genomics
SN 1874-7787
PU Elsevier Science Bv
VL 3
IS 3-4
UT 000285491200002
BP 133
EP 143
DI 10.1016/j.margen.2010.08.005
ID 13799
ER

EF