FN Archimer Export Format
PT J
TI First Evidence of Palytoxin and 42-Hydroxy-palytoxin in the Marine Cyanobacterium Trichodesmium
BT 
AF KERBRAT, Anne Sophie
   AMZIL, Zouher
   PAWLOWIEZ, Ralph
   GOLUBIC, Stjepko
   SIBAT, Manoella
   DARIUS, Helene Taiana
   CHINAIN, Mireille
   LAURENT, Dominique
AS 1:1,2;2:3;3:4;4:5;5:3;6:4;7:4;8:1,6;
FF 1:;2:PDG-RBE-EMP-PHYC;3:;4:;5:PDG-RBE-EMP-PHYC;6:;7:;8:;
C1 Toulouse Univ, UPS, UPS IRD PHARMA DEV UMR152, F-31062 Toulouse 9, France
   IRD, UMR152, Noumea 98848, New Caledonia
   IFREMER, Lab Phycotoxins, F-44311 Nantes 3, France
   ILM, LMT, Papeete 98713, Tahiti, Fr Polynesia
   Boston Univ, Ctr Biol Sci, Boston, MA 02215 USA
   IRD, Papeete 98713, Tahiti, Fr Polynesia
C2 UNIV TOULOUSE, FRANCE
   IRD, FRANCE
   IFREMER, FRANCE
   INST LOUIS MALARDE, FRANCE
   UNIV BOSTON, USA
   IRD, FRANCE
SI NANTES
SE PDG-RBE-EMP-PHYC
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-p187
   copubli-univ-france
   copubli-int-hors-europe
IF 3.854
TC 78
UR https://archimer.ifremer.fr/doc/00040/15143/12576.pdf
LA English
DT Article
DE ;cyanobacteria;Trichodesmium;palytoxin;42-hydroxy-palytoxin;clupeotoxism
AB Marine pelagic diazotrophic cyanobacteria of the genus Trichodesmium (Oscillatoriales) are widespread throughout the tropics and subtropics, and are particularly common in the waters of New Caledonia. Blooms of Trichodesmium are suspected to be a potential source of toxins in the ciguatera food chain and were previously reported to contain several types of paralyzing toxins. The toxicity of water-soluble extracts of Trichodesmium spp. were analyzed by mouse bioassay and Neuroblastoma assay and their toxic compounds characterized using liquid chromatography coupled with tandem mass spectrometry techniques. Here, we report the first identification of palytoxin and one of its derivatives, 42-hydroxy-palytoxin, in field samples of Trichodesmium collected in the New Caledonian lagoon. The possible role played by Trichodesmium blooms in the development of clupeotoxism, this human intoxication following the ingestion of plankton-eating fish and classically associated with Ostreopsis blooms, is also discussed.
PY 2011
PD APR
SO Marine Drugs
SN 1660-3397
PU Mdpi Ag
VL 9
IS 4
UT 000292632300006
BP 543
EP 560
DI 10.3390/md9040543
ID 15143
ER

EF