FN Archimer Export Format
PT J
TI Development of a Mass Sensitive Quartz Crystal Microbalance (QCM)-Based DNA Biosensor Using a 50 MHz Electronic Oscillator Circuit
BT 
AF GARCIA-MARTINEZ, Gonzalo
   ALONSO BUSTABAD, Enrique
   PERROT, Hubert
   GABRIELLI, Claude
   BUCUR, Bogdan
   LAZERGES, Mathieu
   ROSE, Daniel
   RODRIGUEZ-PARDO, Loreto
   FARINA, Jose
   COMPERE, Chantal
   ARNAU VIVES, Antonio
AS 1:1;2:1;3:2,3;4:2;5:2,3;6:2,3;7:2,3;8:1;9:1;10:4;11:5;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:PDG-REM-RDT-IC;11:;
C1 CNRS, LISE, UPR15, F-75252 Paris 05, France
   Univ Vigo, Dpto Tecnol Elect, Vigo 36310, Spain
   Univ Paris 06, F-75252 Paris 05, France
   IFREMER, Ctr Brest, Serv Interfaces & Capteurs, F-29280 Plouzane, France
   Univ Politecn Valencia, Wave Phenomena Grp, Dept Elect Engn, Valencia 46022, Spain
C2 CNRS, FRANCE
   UNIV VIGO, SPAIN
   UNIV PARIS 06, FRANCE
   IFREMER, FRANCE
   UNIV POLITECN VALENCIA, SPAIN
SI BREST
SE PDG-REM-RDT-IC
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-europe
   copubli-univ-france
IF 1.739
TC 43
UR https://archimer.ifremer.fr/doc/00044/15487/12886.pdf
LA English
DT Article
DE ;DNA sequence detection;quartz crystal microbalance;electronic oscillator;sensitivity;frequency noise;resolution
AB This work deals with the design of a high sensitivity DNA sequence detector using a 50 MHz quartz crystal microbalance (QCM) electronic oscillator circuit. The oscillator circuitry is based on Miller topology, which is able to work in damping media. Calibration and experimental study of frequency noise are carried out, finding that the designed sensor has a resolution of 7.1 ng/cm(2) in dynamic conditions (with circulation of liquid). Then the oscillator is proved as DNA biosensor. Results show that the system is able to detect the presence of complementary target DNAs in a solution with high selectivity and sensitivity. DNA target concentrations higher of 50 ng/mL can be detected.
PY 2011
PD AUG
SO Sensors
SN 1424-8220
PU Mdpi Ag
VL 11
IS 8
UT 000294253900020
BP 7656
EP 7664
DI 10.3390/s110807656
ID 15487
ER

EF