FN Archimer Export Format PT J TI Active biomonitoring in Greek coastal waters: Application of the integrated biomarker response index in relation to contaminant levels in caged mussels BT AF TSANGARIS, Catherine HATZIANESTIS, Ioannis CATSIKI, Vassiliki-Angelique KORMAS, Konstantinos Ar STROGYLOUDI, Evangelia NEOFITOU, Christos ANDRAL, Bruno GALGANI, Francois AS 1:1;2:1;3:1;4:2;5:1;6:2;7:3;8:4; FF 1:;2:;3:;4:;5:;6:;7:PDG-ODE-LER-LERPAC;8:PDG-ODE-LER-LERPAC; C1 Hellen Ctr Marine Res, Inst Oceanog, Anavyssos 19013, Greece. Univ Thessaly, Fac Agr Sci, Dept Ichthyol & Aquat Environm, Volos 38446, Greece. IFREMER, Lab Provence Azar Corse, F-83507 La Seyne Sur Mer, France. IFREMER, Lab Environm Ressources Languedoc Roussillon, F-34203 Sete, France. C2 HELLEN CTR MARINE RES, GREECE UNIV THESSALY, GREECE IFREMER, FRANCE IFREMER, FRANCE SI TOULON CORSE SE PDG-ODE-LER-LERPAC IN WOS Ifremer jusqu'en 2018 copubli-europe IF 3.286 TC 49 UR https://archimer.ifremer.fr/doc/00059/17033/14718.pdf LA English DT Article CR MYTIMED 2007 / 1 MYTIMED 2007 / 2 BO L'Europe DE ;Pollution;Biomarkers;Monitoring;Mussel caging;Mytilus galloprovincialis;Mediterranean Sea AB An integrated approach using biomarkers and contaminant levels in mussels Mytilus galloprovincialis L was employed to assess chemical contamination in Greek coastal waters within the framework of the MYTIMED program. Biomarkers (metallothioneins, glutathione S-transferase, catalase, acetylcholinesterase and RNA:DNA ratio) have been previously described in mussels caged at 14 sites in coastal areas influenced by different types of anthropogenic activities. This study applied a biomarker index, the Integrated Biomarker Response (IBR) to summarize biomarker responses and relate stress levels to concentrations of organochlorine compounds (PCBs, DDTs), polycyclic aromatic hydrocarbons (PAHs), and metals (Cu, Ni, Fe, Zn) measured in the mussel tissues. The IBR index indicated environmental stress at sites near cities and industries and was overall related to organic contaminants, but also elevated metal concentrations at certain sites. Slightly increased IBR values at few sites away from known pollution sources were not accompanied with increased contaminant levels suggesting stress possibly caused by natural factors. Results confirmed the usefulness of integration of biological effects measurements and chemical analysis for the assessment of chemical contamination in coastal waters. (C) 2011 Elsevier By. All rights reserved. PY 2011 PD DEC SO Science Of The Total Environment SN 0048-9697 PU Elsevier Science Bv VL 412 UT 000298534300041 BP 359 EP 365 DI 10.1016/j.scitotenv.2011.10.028 ID 17033 ER EF