FN Archimer Export Format
PT J
TI Expression of candidate genes related to metabolism, immunity and cellular stress during massive mortality in the American oyster Crassostrea virginica larvae in relation to biochemical and physiological parameters
BT 
AF GENARD, Bertrand
   MORAGA, Dario
   PERNET, Fabrice
   DAVID, Elise
   BOUDRY, Pierre
   TREMBLAY, Rejean
AS 1:1;2:2;3:3;4:2,4;5:5;6:1;
FF 1:;2:;3:PDG-ODE-LER-LERLR;4:PDG-DGD-DCT-SAFTOULON;5:PDG-RBE-PFOM-PI;6:;
C1 Univ Quebec, Inst Sci Mer, Rimouski, PQ G5L 3A1, Canada.
   Univ Bretagne Occidentale, Inst Univ Europeen Mer, Lab Sci Environm Marin LEMAR, Plouzane, France.
   IFREMER, Lab Environm Ressources Languedoc Roussillon, Sete, France.
   Univ Reims, Unite Rech Vigne & Vins Champagne Stress & Enviro, UPRES EA2069, Lab Ecol Ecotoxicol, F-51687 Reims 02, France.
   IFREMER, Lab Physiol Invertebres, F-29280 Plouzane, France.
C2 UNIV QUEBEC, CANADA
   UBO, FRANCE
   IFREMER, FRANCE
   UNIV REIMS, FRANCE
   IFREMER, FRANCE
SI BREST
   SETE
   TOULON
SE IUEM
   PDG-ODE-LER-LERLR
   PDG-DGD-DCT-SAFTOULON
   PDG-RBE-PFOM-PI
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
   copubli-int-hors-europe
IF 2.2
TC 15
UR https://archimer.ifremer.fr/doc/00075/18585/16138.pdf
LA English
DT Article
DE ;Massive mortality;Relative gene expression;Metabolism;Immunity;Cellular stress;Larvae
AB Quantification of mRNA of genes related to metabolism, immunity and cellular stress was examined in relation to a massive mortality event during the culture of American oyster larvae, Crassostrea virginica which was probably, in regard to previous microbiological analysis, induced by vibrio infection. To document molecular changes associated with the mortality event, mRNA levels were compared to biochemical and physiological data, previously described in a companion paper. Among the 18 genes studied, comparatively to the antibiotic control, 10 showed a lower relative gene expression when the massive mortality occurred. Six of them are presumed to be related to metabolism, corroborating the metabolic depression associated with the mortality event suggested by biochemical and physiological analyses. Relationships between the regulation of antioxidant enzyme activities, lipid peroxidation, and the mRNA abundance of genes linked to oxidative stress, cytoprotection, and immune response are also discussed. Finally, we observed an increase in the transcript abundance of two genes involved in apoptosis and cell regulation simultaneously with mortality, suggesting that these processes might be linked.
PY 2012
PD MAY
SO Gene
SN 0378-1119
PU Elsevier Science Bv
VL 499
IS 1
UT 000303621400010
BP 70
EP 75
DI 10.1016/j.gene.2012.02.021
ID 18585
ER

EF