FN Archimer Export Format
PT J
TI Detection of early effects of a single herbicide (diuron) and a mix of herbicides and pharmaceuticals (diuron, isoproturon, ibuprofen) on immunological parameters of Pacific oyster (Crassostrea gigas) spat
BT 
AF LUNA-ACOSTA, Andrea
   RENAULT, Tristan
   THOMAS-GUYON, Helene
   FAURY, Nicole
   SAULNIER, Denis
   BUDZINSKI, Helene
   LE MENACH, K.
   PARDON, P.
   FRUITIER-ARNAUDIN, I.
   BUSTAMANTE, Paco
AS 1:1,3;2:2,3;3:1,3;4:2,3;5:2,3;6:4;7:4;8:4;9:1,3;10:1,3;
FF 1:;2:PDG-RBE-AGSAE-LGP;3:;4:PDG-RBE-AGSAE-LGP;5:PDG-RBE-RMPF-EP;6:;7:;8:;9:;10:;
C1 Univ La Rochelle, CNRS, Littoral Environm & Soc LIENSs, UMR 7266, F-17042 La Rochelle 01, France.
   IFREMER, LGP, F-17390 Ronce Les Bains, La Tremblade, France.
   Federat Rech Environm Dev Durable, FR 3097, F-17042 La Rochelle 01, France.
   Univ Bordeaux 1, CNRS, Lab Physicotoxicochim Environm LPTC, EPOC,UMR 5805, F-33405 Talence, France.
C2 UNIV LA ROCHELLE, FRANCE
   IFREMER, FRANCE
   FREDD, FRANCE
   UNIV BORDEAUX, FRANCE
SI LA TREMBLADE
   TAHITI
SE PDG-RBE-AGSAE-LGP
   PDG-RBE-RMPF-EP
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 3.14
TC 41
UR https://archimer.ifremer.fr/doc/00083/19435/17475.pdf
LA English
DT Article
DE ;Bivalve;Pollution;Gene expression;Laccase;Superoxide dismutase;Phagocytosis
AB In the context of massive summer mortality events of the Pacific oyster Crassostrea gigas, the aim of this study was to investigate the early effects on genes, enzymes and haemocyte parameters implicated in immune defence mechanisms in C. gigas oysters exposed to a potentially hostile environment, i.e. to an herbicide alone or within a mixture. Following 2 h of exposure to the herbicide diuron at 1 mu g L-1 the repression of different genes implicated in immune defence mechanisms in the haemocytes and the inhibition of enzyme activities, such as laccase-type phenoloxidase (PO) in the plasma, were observed. The inhibition of superoxide dismutase (SOD) activity in the plasma was also observed after 6 and 24 h of exposure. In the mixture with the herbicides diuron and isoproturon, and the pharmaceutical ibuprofen, catecholase-type PO activity in the plasma and the percentage of phagocytosis in the haemocytes were reduced after 6 h of exposure. Our results showed that early effects on molecular, biochemical and cellular parameters can be detected in the presence of diuron alone or within a mixture, giving an insight of its potential effect in situations that can be found in natural environments, i.e. relatively high concentrations for short periods of time. (C) 2012 Elsevier Ltd. All rights reserved.
PY 2012
PD JUL
SO Chemosphere
SN 0045-6535
PU Pergamon-elsevier Science Ltd
VL 87
IS 11
UT 000303640200021
BP 1335
EP 1340
DI 10.1016/j.chemosphere.2012.02.022
ID 19435
ER

EF