FN Archimer Export Format PT J TI Transmission of viruses through shellfish: when specific ligands come into play BT AF LE GUYADER, Soizick ATMAR, Robert L. LE PENDU, Jacques AS 1:1;2:2;3:3; FF 1:PDG-RBE-EMP-MICLNR;2:;3:; C1 IFREMER, Microbiol Lab, F-44311 Nantes 03, France. Baylor Coll Med, Dept Med, Houston, TX 77030 USA. Univ Nantes, INSERM, Inst Rech Therapeut, U892, F-44007 Nantes 1, France. C2 IFREMER, FRANCE BAYLOR COLL MED, USA UNIV NANTES, FRANCE SI NANTES SE PDG-RBE-EMP-MICLNR IN WOS Ifremer jusqu'en 2018 copubli-france copubli-univ-france copubli-int-hors-europe IF 2.46 TC 110 UR https://archimer.ifremer.fr/doc/00114/22516/20238.pdf LA English DT Article AB Shellfish are known as vectors for human pathogens and despite regulation based on enteric bacteria they are still implicated in viral outbreaks. Among shellfish, oysters are the most common vector of contamination, and the pathogens most frequently involved in these outbreaks are noroviruses, responsible for acute gastroenteritis in humans. Analysis of shellfish-related outbreak data worldwide show an unexpected high proportion of NoV GI strains. Recent studies performed in vitro, in vivo and in the environment indicate that oysters are not just passive filters, but can selectively accumulate norovirus strains based on viral carbohydrate ligands shared with humans. These observations contribute to explain the GI bias observed in shellfish-related outbreaks compared to other outbreaks. PY 2012 PD FEB SO Current Opinion In Virology SN 1879-6257 PU Elsevier Sci Ltd VL 2 IS 1 UT 000312112600015 BP 103 EP 110 DI 10.1016/j.coviro.2011.10.029 ID 22516 ER EF