FN Archimer Export Format
PT J
TI Insights into the antiviral functions of the RNAi machinery in penaeid shrimp
BT 
AF LABREUCHE, Yannick
   WARR, Gregory W.
AS 1:1;2:2,3;
FF 1:PDG-RBE-LEADNC;2:;
C1 IFREMER, Dept Lagons Ecosyst & Aquaculture Durable Nouvell, Noumea 98846, New Caledonia.
   Natl Sci Fdn, Div Mol & Cellular Biosci, Arlington, VA 22230 USA.
   Med Univ S Carolina, Dept Biochem & Mol Biol, Charleston, SC 29425 USA.
C2 IFREMER, FRANCE
   NATL SCI FDN, USA
   UNIV MED S CAROLINA, USA
SI SAINT VINCENT
SE PDG-RBE-LEADNC
IN WOS Ifremer jusqu'en 2018
   copubli-int-hors-europe
IF 3.034
TC 26
UR https://archimer.ifremer.fr/doc/00119/23063/20899.pdf
LA English
DT Article
DE ;Shrimp;Innate immune response;In vertebrate immunity;RNA interference;Virus
AB Over the last decade, RNA interference pathways have emerged in eukaryotes as critical regulators of many diverse biological functions including, among others, transcriptional gene regulation, post-transcriptional gene silencing, heterochromatin remodelling, suppression of transposon activity, and antiviral defences. Although this gene silencing process has been reported to be relatively well conserved in species of different phyla, there are important discrepancies between plants, invertebrates and mammals. In penaeid shrimp, the existence of an intact and functional RNAi machinery is supported by a rapidly growing body of evidence. However, the extent to which this process participates to the host immune responses remains poorly defined in this non-model organism. This review summarizes our current knowledge of RNAi mechanisms in shrimp and focuses on their implication in antiviral activities and shrimp immune defences.
PY 2013
PD APR
SO Fish & Shellfish Immunology
SN 1050-4648
PU Academic Press Ltd- Elsevier Science Ltd
VL 34
IS 4
UT 000325955900007
BP 1002
EP 1010
DI 10.1016/j.fsi.2012.06.008
ID 23063
ER

EF