FN Archimer Export Format
PT J
TI Phylodynamics and human-mediated dispersal of a zoonotic virus.
BT 
AF TALBI, Chiraz
   LEMEY, Philippe
   SUCHARD, Marc A.
   ABDELATIF, Elbia
   ELHARRAK, Mehdi
   NOURLIL, Jalal
   ABDELLAH, Faouzi
   ECHEVARRIA, Juan E.
   MORON, Sonia Vasquez
   RAMBAUT, Andrew
   CAMPIZ, Nicholas
   TATEM, Andrew J.
   HOLMES, Edward
   BOURHY, Hervé
AS 1:1;2:2;3:3;4:4;5:5;6:6;7:6;8:7;9:7;10:8,9;11:10;12:10,11;13:9,12;14:1;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;11:;12:;13:;14:;
C1 Institut Pasteur, Unit Lyssavirus Dynamics and Host Adaptation, WHO Collaborating Centre for Reference and Research on Rabies, Paris, France
   Rega Institute, Katholieke Universiteit Leuven, Leuven, Belgium
   Departments of Biomathematics and Human Genetics, David Geffen School of Medicine, and Department of Biostatistics, School of Public Health, University of California, Los Angeles, Los Angeles, California, United States of America
   Institut Pasteur d’Alge´ rie, Laboratoire de la Rage, Recherche et Diagnostic, Alger, Alge´ rie
   Biopharma Laboratoire, Rabbat, Maroc
   Institut Pasteur du Maroc, Laboratoire de Virologie Me´dicale, Casablanca, Maroc
   Instituto de Salud Carlos III, Servicio de Microbiologı´a Diagno´ stica, Madrid, Spain
   of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom
   Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
   Department of Geography, University of Florida, Gainesville, Florida, United States of America
   Emerging Pathogens Institute, University of Florida, Gainesville, Florida, United States of America
   Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
C2 INST PASTEUR, FRANCE
   REGA INSTITUTE, BELGIUM
   UNIV CALIF LOS ANGELES, USA
   INST PASTEUR ALGERIE, ALGERIE
   BIOPHARMA LAB, MAROC
   INST PASTEUR MAROC, MAROC
   INST SALUD CARLOS III, SPAIN
   UNIV EDINBURGH, UK
   NATL INST HLTH, USA
   UNIV FLORIDA, USA
   UNIV FLORIDA, USA
   UNIV PENN STATE, USA
IF 8.14
TC 0
UR https://archimer.ifremer.fr/doc/00139/24992/23090.pdf
LA English
DT Article
AB Understanding the role of humans in the dispersal of predominately animal pathogens is essential for their control. We used newly developed Bayesian phylogeographic methods to unravel the dynamics and determinants of the spread of dog rabies virus (RABV) in North Africa. Each of the countries studied exhibited largely disconnected spatial dynamics with major geo-political boundaries acting as barriers to gene flow. Road distances proved to be better predictors of the movement of dog RABV than accessibility or raw geographical distance, with occasional long distance and rapid spread within each of these countries. Using simulations that bridge phylodynamics and spatial epidemiology, we demonstrate that the contemporary viral distribution extends beyond that expected for RABV transmission in African dog populations. These results are strongly supportive of human-mediated dispersal, and demonstrate how an integrated phylogeographic approach will turn viral genetic data into a powerful asset for characterizing, predicting, and potentially controlling the spatial spread of pathogens
PY 2010
SO PLOS pathogens
SN 1553-7374
PU Public Library Science
VL 6
IS 10
BP 1
EP 10
DI 10.1371/journal.ppat.1001166
ID 24992
ER

EF