FN Archimer Export Format
PT C
TI Maldi mass spectrometry imaging applied to small molecules localization
BT 
AF GUITTON, Yann
   MONDEGUER, Florence
   NICOLAU, Elodie
   ROYER, Florence
   HILBERT, Jean-Louis
   FOURNIER, Isabelle
   WISZTORSKI, Maxence
AS 1:1;2:3;3:3;4:3;5:1;6:2;7:2;
FF 1:;2:PDG-ODE-LITTORAL-PHYC;3:PDG-ODE-LITTORAL-PHYC;4:PDG-RBE-LEADNC;5:;6:;7:;
C1 INRA, USTL UMR SADV 1281, Stress Abiotiques et Différenciation des Végétaux Cultivés, Université Lille Nord de France, Lille 1, SN2, F-59655 Villeneuve d’Ascq, France
   Université Lille Nord de France, MALDI Imaging Team, Laboratoire de Spectrométrie de masse Biologique, Fondamentale, Appliquée, EA-4550, Lille 1, SN3, F-59655 Villeneuve d’Ascq, France
   IFREMER , Laboratoire Phycotoxines, Rue de l’ile d’Yeu, BP 21105 44311 Nantes, France
C2 INRA, FRANCE
   UNIV LILLE, FRANCE
   IFREMER, FRANCE
SI NANTES
   SAINT VINCENT
SE PDG-ODE-LITTORAL-PHYC
   PDG-RBE-LEADNC
UR https://archimer.ifremer.fr/doc/00179/29041/27479.pdf
LA English
DT Poster
AB MALDI Mass Spectrometry Imaging (MALDI-MSI) is a two-dimensional MALDI mass spectrometric technique used to visualize the spatial distribution of a large variety of biological molecules (from small metabolites to large proteins) without extraction, purification, separation or labelling of biological samples. Since its introduction by Caprioli et al in 1997, it has become one of the most important molecular histology methods for biomarker hunting and for understanding the spatial distribution of biomolecules in various tissues. MALDI-MSI is thus ideal for complementing the expanding field of metabolomics. Despite the fact that MALDI-MSI have been very successfully applied in divers studies (even in clinical applications) its use remains far from routine, and there is still a need to adapt protocols to suit specific tissues4 or metabolites. Here we describe the methodology of MALDI-MSI with examples taken from applications in plant (Cichorium intybus) and in seashell (Mytilus edulis).
PY 2012
PD MAY
ID 29041
ER

EF