FN Archimer Export Format
PT J
TI Design Polysaccharides of Marine Origin: Chemical Modifications to Reach Advanced Versatile Compounds
BT 
AF CHOPIN, Nathalie
   GUILLORY, Xavier
   WEISS, Pierre
   LE BIDEAU, Jean
   COLLIEC-JOUAULT, Sylvia
AS 1:1,2;2:1;3:3;4:2;5:1;
FF 1:;2:PDG-RBE-BRM-LEMMMB;3:;4:;5:PDG-RBE-BRM-LEMMMB;
C1 IFREMER, Inst Francais Rech Exploitat Mer, Lab Biotechnol & Mol Mat, F-44311 Nantes 03, France.
   Univ Nantes, CNRS, Inst Mat Jean Rouxel, F-44322 Nantes 3, France.
   Univ Nantes, INSERM, LIAOD, U791, F-44042 Nantes 1, France.
C2 IFREMER, FRANCE
   UNIV NANTES, FRANCE
   UNIV NANTES, FRANCE
SI NANTES
   UNIV-FRANCAISE
SE PDG-RBE-BRM-LEMMMB
   UNIV-FRANCAISE
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 2.157
TC 18
UR https://archimer.ifremer.fr/doc/00199/31027/29902.pdf
LA English
DT Article
DE ;Alginates;carrageenans;chemical modification;chitin;chitosan;grafting;marine polysaccharide;polymer
AB Polysaccharides are among the most abundant macromolecules on Earth. These polymers are easily obtained from various marine resources such as algae, microorganisms and crustacean shells. The structure of these natural carbohydrates is innovative and quite complex. Marine biopolymers represent key scaffolds toward large challenging fields, such as biomedical applications (glycosaminoglycans, regenerative medicine and drug delivery) and tailored biomaterials. Chemical modifications can be applied to modify their final properties in a specific purpose. New functional glycans are achievable and represent a real potential with their intrinsic biocompatibility and biodegradability. Hydroxyl groups are ubiquitous in polysaccharides structure and involved in most of the chemical modifications. The most useful functionalities are ester, ether, amide, amine and alkyl groups. The starting materials could be a natural or depolymerized polymers and the reaction considered with a regioselective point of view. In this review, we will focus on chitin polysaccharide, which is extracted according to industrial processing from exoskeleton of several marine crustaceans. A subsequent deacylation provides chitosan. This marine polysaccharide is very similar to cellulose, a widespread fiber plant organic polymer, except for an amine group on the C2 position instead of a hydroxyl group. Furthermore, seaweeds provide the most abundant sources of polysaccharides: alginates, agar/agarose, carrageenans and fuco dans. In order to improve the original physicochemical and biochemical properties, we will highlight the chemical modifications involving the listed marine polysaccharides of interest.
PY 2014
SO Current Organic Chemistry
SN 1385-2728
PU Bentham Science Publ Ltd
VL 18
IS 7
UT 000337249400008
BP 867
EP 895
DI 10.2174/138527281807140515152334
ID 31027
ER

EF