Thermal Stress Triggers Broad Pocillopora damicornis Transcriptomic Remodeling, while Vibrio coralliilyticus Infection Induces a More Targeted Immuno-Suppression Response
| Type | Article | ||||||||
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| Date | 2014-09 | ||||||||
| Language | English | ||||||||
| Author(s) | Vidal-Dupiol Jeremie1, 2, Dheilly Nolwenn M.1, 2, Rondon Rodolfo1, 2, 3, Grunau Christoph1, 2, Cosseau Celine1, 2, Smith Kristina M.4, Freitag Michael4, Adjeroud Mehdi5, Mitta Guillaume1, 2 | ||||||||
| Affiliation(s) | 1 : CNRS, UMR 5244, Perpignan, France. 2 : Univ Perpignan, UMR 5244, F-66025 Perpignan, France. 3 : IFREMER, UM2,CNRS, UMR 5119, Montpellier, France. 4 : Oregon State Univ, Dept Biochem & Biophys, Ctr Genome Res & Biocomp, Corvallis, OR 97331 USA. 5 : Inst Rech DEv, Biocomplex Ecosyst Coralliens Indo Pacifique U227, Lab Excellence CORAIL, Banyuls Sur Mer, France. |
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| Source | Plos One (1932-6203) (Public Library Science), 2014-09 , Vol. 9 , N. 9 , P. 1-15 | ||||||||
| DOI | 10.1371/journal.pone.0107672 | ||||||||
| WOS© Times Cited | 40 | ||||||||
| Note | Table S1 : http://www.plosone.org/article/fetchSingleRepresentation.action?uri=info:doi/10.1371/journal.pone.0107672.s001 Table S2 : http://www.plosone.org/article/fetchSingleRepresentation.action?uri=info:doi/10.1371/journal.pone.0107672.s002 Table S3 : http://www.plosone.org/article/fetchSingleRepresentation.action?uri=info:doi/10.1371/journal.pone.0107672.s003 Table S4 : http://www.plosone.org/article/fetchSingleRepresentation.action?uri=info:doi/10.1371/journal.pone.0107672.s004 | ||||||||
| Abstract | Global change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. This has resulted in increased disease in natural plant and animal populations worldwide, including scleractinian corals. While the effects of temperature increase on immunity and pathogen virulence have been clearly identified, their interaction, synergy and relative weight during pathogenesis remain poorly documented. We investigated these phenomena in the interaction between the coral Pocillopora damicornis and the bacterium Vibrio coralliilyticus, for which the infection process is temperature-dependent. We developed an experimental model that enabled unraveling the effects of thermal stress, and virulence vs. non-virulence of the bacterium. The physiological impacts of various treatments were quantified at the transcriptome level using a combination of RNA sequencing and targeted approaches. The results showed that thermal stress triggered a general weakening of the coral, making it more prone to infection, non-virulent bacterium induced an 'efficient' immune response, whereas virulent bacterium caused immuno-suppression in its host. | ||||||||
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