FN Archimer Export Format
PT J
TI Hypoxic episode during the larval period has long-term effects on European sea bass juveniles (Dicentrarchus labrax)
BT 
AF VANDERPLANCKE, Gwenaelle
   CLAIREAUX, Guy
   QUAZUGUEL, Patrick
   MADEC, Lauriane
   FERRARESSO, Serena
   SEVERE, Armelle
   ZAMBONINO-INFANTE, Jose-Luis
   MAZURAIS, David
AS 1:1;2:1,2;3:1;4:1;5:3;6:1;7:1;8:1;
FF 1:PDG-RBE-PFOM-ARN;2:;3:PDG-RBE-PFOM-ARN;4:PDG-RBE-PFOM-ARN;5:;6:PDG-RBE-PFOM-ARN;7:PDG-RBE-PFOM-ARN;8:PDG-RBE-PFOM-ARN;
C1 IFREMER, Ctr Brest, LEMAR UMR CNRS UBO IRD 6539, ZI La Pointe Du Diable,CS 10070, F-29280 Plouzane, France.
   IFREMER, UBO, LEMAR UMR CNRS UBO IRD 6539, ZI La Pointe Du Diable, F-29280 Plouzane, France.
   Univ Padua, Dept Comparat Biomed & Food Sci, I-35020 Legnaro, Italy.
C2 IFREMER, FRANCE
   UBO, FRANCE
   UNIV PADUA, ITALY
SI BREST
SE PDG-RBE-PFOM-ARN
UM LEMAR
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-europe
   copubli-univ-france
IF 2.375
TC 32
UR https://archimer.ifremer.fr/doc/00254/36517/36676.pdf
LA English
DT Article
AB Hypoxia episodes have been generally studied over the last decade for their lethal consequences in coastal areas, which are nurseries for several fish species. The possible long-lasting effects of non-lethal hypoxia exposures at larval stage are, however, poorly documented. We investigated the long-lasting phenotypic impact of an experimental exposure to moderate hypoxia (40 % air saturation) between 30 and 38 days post-hatching in European sea bass (Dicentrarchus labrax). At the juvenile stage, our data indicate that this early hypoxia exposure impacted on juvenile growth rate but not on hypoxia tolerance. Growth depression was associated with a regulation of metabolism as suggested by a decrease in blood glycaemia, a decreased hepatic expression of the glucose transporter glut2 and of acaca involved in fatty acid synthesis as well as an increased hepatic expression of glycolytic ldh-a, which is a target gene of hypoxia inducible factors (HIFs). Interestingly, while fish were not exposed to hypoxia, the cellular oxygen sensor egln3 gene, which is also a target of HIFs, exhibited higher expression level in the hepatic tissue of juveniles that have experienced hypoxia at larval stage. Even if further studies are needed to evaluate the functional significance of such effects and to decipher the underlying molecular mechanisms, the present data evidence that early life exposure to a hypoxia event has long-lasting impact on sea bass juvenile physiology.
PY 2015
PD FEB
SO Marine Biology
SN 0025-3162
PU Springer Heidelberg
VL 162
IS 2
UT 000348564300012
BP 367
EP 376
DI 10.1007/s00227-014-2601-9
ID 36517
ER

EF