FN Archimer Export Format
PT J
TI Interaction between toxic dinoflagellate Alexandrium catenella exposure and disease associated with herpesvirus OsHV-1μVar in Pacific oyster spat Crassostrea gigas
BT 
AF LASSUDRIE, Malwenn
   SOUDANT, Philippe
   NICOLAS, Jean-Louis
   FABIOUX, Caroline
   LAMBERT, Christophe
   MINER, Philippe
   LE GRAND, Jacqueline
   PETTON, Bruno
   HEGARET, Helene
AS 1:1;2:1;3:2;4:1;5:1;6:2;7:3;8:3;9:1;
FF 1:;2:;3:PDG-RBE-PFOM-PI;4:;5:;6:PDG-RBE-PFOM-PI;7:PDG-RBE-PFOM-PI;8:PDG-RBE-PFOM-PI;9:;
C1 Inst Univ Europeen Mer, UMR CNRS UBO IRD IFREMER 6539, Lab Sci Environm Marin LEMAR, F-29280 Plouzane, France.
   IFREMER, Lab Sci Environm Marin LEMAR, IRD,CS 10070, Ctr Bretagne,ZI Pointe du Diable,CNRS,UMR UBO 653, F-29280 Plouzane, France.
   IFREMER, Lab Sci Environm Marin LEMAR, IRD, CNRS,UMR UBO 6539, F-29840 Argenton En Landunvez, France.
C2 UBO, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
   CNRS, FRANCE
SI BREST
   ARGENTON
SE PDG-RBE-PFOM-PI
UM LEMAR
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 2.664
TC 23
UR https://archimer.ifremer.fr/doc/00269/38000/36101.pdf
LA English
DT Article
DE ;Crassostrea gigas;OsHV-1 mu Var;Harmful algal blooms;Alexandrium;Host-pathogen interaction;PST accumulation
AB Blooms of toxic dinoflagellates can co-occur with mass mortality events associated with herpesvirus OsHV-1 μVar infection that have been decimating Pacific oyster Crassostrea gigas spat and juveniles every summer since 2008 in France. This study investigated the possible effect of a harmful dinoflagellate, Alexandrium catenella, a producer of Paralytic Shellfish Toxins (PSTs), upon the oyster spat–herpesvirus interaction. Oyster spat from a hatchery were challenged by cohabitation with oysters contaminated in the field with OsHV-1 μVar and possibly other pathogens. Simultaneously, the oysters were exposed to cultured A. catenella. Infection with OsHV-1 μVar and PST accumulation were measured after 4 days of experimental exposure.  Exposure to Alexandrium catenella modified the host–pathogen interaction by reducing prevalence of OsHV-1 μVar infection. In addition, oysters challenged with OsHV-1 μVar and possibly other pathogens from the environment accumulated smaller amounts of PSTs than unchallenged oysters. Three possible mechanisms are suggested by these results: (i) possible direct interactions between A. catenella and herpesvirus (or associated pathogens) could reduce viral transmission and algal availability for oyster consumption; (ii) oyster feeding behavior or digestive functions may have been altered, thus decreasing both uptake of viral particles and consumption or digestion of toxic algae and consequent toxin accumulation; (iii) immuno-activation by A. catenella could enhance defense efficiency against OsHV-1 μVar infection. These findings suggest further research on relationships between OsHV-1 μVar and toxic dinoflagellates and their combined effects upon disease transmission and proliferation processes, as well as on oyster physiological and immunological involvement in this complex, tripartite interaction.
PY 2015
PD MAY
SO Harmful Algae
SN 1568-9883
PU Elsevier Science Bv
VL 45
UT 000358098200006
BP 53
EP 61
DI 10.1016/j.hal.2015.04.007
ID 38000
ER

EF