FN Archimer Export Format
PT J
TI New Insight for the Genetic Evaluation of Resistance to Ostreid Herpesvirus Infection, a Worldwide Disease, in Crassostrea gigas
BT 
AF DEGREMONT, Lionel
   LAMY, Jean-Baptiste
   PEPIN, Jean-Francois
   TRAVERS, Marie-Agnes
   RENAULT, Tristan
AS 1:1;2:1;3:2;4:1;5:1;
FF 1:PDG-RBE-SG2M-LGPMM;2:PDG-RBE-SG2M-LGPMM;3:PDG-ODE-LITTORAL-LERPC;4:PDG-RBE-SG2M-LGPMM;5:PDG-RBE;
C1 Inst Francais Rech Exploitat Mer, Lab Genet & Pathol Mollusques Marins, La Tremblade, France.
   Inst Francais Rech Exploitat Mer, Lab Environm Resources Pertuis Charentais, La Tremblade, France.
C2 IFREMER, FRANCE
   IFREMER, FRANCE
SI LA TREMBLADE
   NANTES
SE PDG-RBE-SG2M-LGPMM
   PDG-ODE-LITTORAL-LERPC
   PDG-RBE
IN WOS Ifremer jusqu'en 2018
IF 3.057
TC 52
UR https://archimer.ifremer.fr/doc/00269/38066/36178.pdf
LA English
DT Article
AB The Pacific oyster, Crassostrea gigas, is the most important commercial oyster species cultivated in the world. Meanwhile, the ostreid herpesvirus 1 (OsHV-1) is one of the major pathogens affecting the Pacific oyster, and numerous mortality outbreaks related to this pathogen are now reported worldwide. To assess the genetic basis of resistance to OsHV-1 infection in spat C. gigas and to facilitate breeding programs for such a trait, if any exist, we compared the mortality of half- and full-sib families using three field methods and a controlled challenge by OsHV-1 in the laboratory. In the field, three methods were tested: (A) one family per bag; (B) one family per small soft mesh bag and all families inside one bag; (C) same as the previous methods but the oysters were individually labelled and then mixed. The mean mortality ranged from 80 to 82% and was related to OsHV-1 based on viral DNA detection. The narrow-sense heritability for mortality, and thus OsHV-1 resistance, ranged from 0.49 to 0.60. The high positive genetic correlations across the field methods suggested no genotype by environment interaction. Ideally, selective breeding could use method B, which is less time- and space-consuming. The narrow sense heritability for mortality under OsHV-1 challenge was 0.61, and genetic correlation between the field and the laboratory was ranged from 0.68 to 0.75, suggesting a weak genotype by environment interaction. Thus, most of families showing the highest survival performed well in field and laboratory conditions, and a similar trend was also observed for families with the lowest survival. In conclusion, this is the first study demonstrating a large additive genetic variation for resistance to OsHV-1 infection in C. gigas, regardless of the methods used, which should help in selective breeding to improve resistance to viral infection in C. gigas.
PY 2015
PD JUL
SO Plos One
SN 1932-6203
PU Public Library Science
VL 10
IS 6
UT 000355700700078
DI 10.1371/journal.pone.0127917
ID 38066
ER

EF