FN Archimer Export Format PT J TI Can survival of European flat oysters following experimental infection with Bonamia ostreae be predicted using QTLs? BT AF HARRANG, Estelle HEURTEBISE, Serge FAURY, Nicole ROBERT, Maeva ARZUL, Isabelle LAPEGUE, Sylvie AS 1:1;2:1;3:1;4:1;5:1;6:1; FF 1:PDG-RBE-AGSAE-LGP;2:PDG-RBE-SG2M-LGPMM;3:PDG-RBE-SG2M-LGPMM;4:;5:PDG-RBE-SG2M-LGPMM;6:PDG-RBE-SG2M; C1 IFREMER, SG2M, LGPMM, F-17390 La Tremblade, France. C2 IFREMER, FRANCE SI LA TREMBLADE SE PDG-RBE-AGSAE-LGP PDG-RBE-SG2M-LGPMM PDG-RBE-SG2M IN WOS Ifremer jusqu'en 2018 IF 1.893 TC 11 UR https://archimer.ifremer.fr/doc/00271/38244/36429.pdf LA English DT Article DE ;Ostrea edulis;Single Nucleotide Polymorphism;Disease resistance;Genetic and QTL mapping;Candidate genes AB The present study identifies quantitative trait loci (QTLs) in response to an experimental infection with the parasite responsible for bonamiosis, Bonamia ostreae, in two segregating families of the European flat oyster, Ostrea edulis. We first constructed a genetic-linkage map for each studied family and improved the existing genetic-linkage map for the European flat oyster with a set of SNP markers. This latter map now combines the best accuracy and the best estimate of the genome coverage available for an oyster species. Secondly, by comparing the QTLs detected in this study with those previously published for O. edulis in similar experimental conditions, we identified several potential QTLs that were identical between the different families, and also new specific QTLs. We also detected, within the confidence interval of several QTL regions, some previously predicted candidate genes differentially expressed during an infection with B. ostreae, providing new candidate genome regions which should now be studied more specifically. PY 2015 PD NOV SO Aquaculture SN 0044-8486 PU Elsevier Science Bv VL 448 UT 000360189000065 BP 521 EP 530 DI 10.1016/j.aquaculture.2015.06.019 ID 38244 ER EF