FN Archimer Export Format
PT J
TI Highly diverse recombining populations of Vibrio cholerae and Vibrio parahaemolyticus in French Mediterranean coastal lagoons
BT 
AF ESTEVES, Kevin
   MOSSER, Thomas
   AUJOULAT, Fabien
   HERVIO-HEATH, Dominique
   MONFORT, Patrick
   JUMAS-BILAK, Estelle
AS 1:1;2:1;3:1;4:2;5:1;6:1,3;
FF 1:;2:;3:;4:PDG-RBE-SG2M-LSEM;5:PDG-ODE-LITTORAL-LERBO;6:;
C1 Univ Montpellier, Ctr Natl Rech, HydroSci Montpellier,IRD, UMR 5569,Team Pathogenes Hydriques Sante Environm, F-34059 Montpellier, France.
   Ifremer, RBE, SG2M, Lab Sante Environm & Microbiol, Plouzane, France.
   CHU Montpellier, Dept Hyg Hsp, Montpellier, France.
C2 UNIV MONTPELLIER, FRANCE
   IFREMER, FRANCE
   CHU MONTPELLIER, FRANCE
SI BREST
   CONCARNEAU
SE PDG-RBE-SG2M-LSEM
   PDG-ODE-LITTORAL-LERBO
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 4.165
TC 20
UR https://archimer.ifremer.fr/doc/00274/38528/37039.pdf
LA English
DT Article
DE ;Vibrio;human pathogens;French coastal lagoons;phylogeny;recombination;multi-locus sequence analysis;virulence factor
AB Vibrio parahaemolyticus and Vibrio cholerae are ubiquitous to estuarine and marine environments. Thes two species found in Mediterranean coastal systems can induce infection in humans. Environmental isolates of V. cholerae (n = 109) and V. parahaemotycius (n = 89) sampled at different dates, stations and water salinities were investigated for virulence genes and by a mutilocus sequence-based analysis (MLSA). V. cholerae isolate were all ctxA negative and only one isolate of V. parahaemolyticus displayed trh2 gene. Most Sequence Types (ST) corresponded to uique ST isolated at one date or one station. Frequent recombination events were detected among different pathogenic species, V. parahaemotyticus, V. cholerae, Vibrio mimicus, and Vibrio metoecus. Recombination had a major impact on the diversification of lineages. The genetic diversity assessed by the number of ST/strain was higher in low salinity condition for V. parahaemolyticus and V. cholerae whereas the frequency of recombination events in V. cholerae was lower in low salinity condition. Mediterranean coastal lagoon systems housed V. cholerae and V. parahaemotyticus with genetic divesities equivalent to the worldwide diversity described so far. The presence of STs found in human infections as well as the frequency of recombination events in enviromental vibrios populations could predict a potential epidemiological risk.
PY 2015
PD JUN
SO Frontiers In Microbiology
SN 1664-302X
PU Frontiers Media Sa
VL 6
UT 000358650400001
DI 10.3389/fmicb.2015.00708
ID 38528
ER

EF