FN Archimer Export Format PT J TI Mass mortality in bivalves and the intricate case of the Pacific oyster, Crassostrea gigas BT AF BARBOSA-SOLOMIEU, Valerie RENAULT, Tristan TRAVERS, Marie-Agnes AS 1:1;2:2;3:2; FF 1:PDG-RBE-SG2M-LGPMM;2:PDG-RBE;3:PDG-RBE-SG2M-LGPMM; C1 Univ Bretagne Occidentale, Direct Europe & Int, F-29238 Brest 3, France. IFREMER, Unite Sante Genet Microbiol Mollusques SG2M, LGPMM, F-17390 La Tremblade, France. C2 UBO, FRANCE IFREMER, FRANCE SI LA TREMBLADE NANTES SE PDG-RBE-SG2M-LGPMM PDG-RBE IN WOS Ifremer jusqu'en 2018 copubli-france copubli-univ-france IF 2.198 TC 109 UR https://archimer.ifremer.fr/doc/00274/38534/37051.pdf LA English DT Article DE ;Pacific oyster;Spat;OsHV-1;Vibrio aestuarianus;Mortality AB Massive mortality outbreaks in cultured bivalves have been reported worldwide and they have been associated with infection by a range of viral and bacterial pathogens. Due to their economic and social impact, these episodes constitute a particularly sensitive issue in Pacific oyster (Crassostrea gigas) production. Since 2008, mortality outbreaks affecting C. gigas have increased in terms of intensity and geographic distribution. Epidemiologic surveys have lead to the incrimination of pathogens, specifically OsHV-1 and bacteria of the Vibrio genus, in particular Vibrio aestuarianus. Pathogen diversity may partially account for the variability in the outcome of infections. Host factors (age, reproductive status…) including their genetic background that has an impact on host susceptibility towards infection, also play a role herein. Finally, environmental factors have significant effects on the pathogens themselves, on the host and on the host-pathogen interaction. Further knowledge on pathogen diversity, classification, and spread, may contribute towards a better understanding of this issue and potential ways to mitigate the impact of these outbreaks. PY 2015 PD OCT SO Journal Of Invertebrate Pathology SN 0022-2011 PU Academic Press Inc Elsevier Science VL 131 UT 000363077300002 BP 2 EP 10 DI 10.1016/j.jip.2015.07.011 ID 38534 ER EF