Use of Natural Antimicrobial Peptides and Bacterial Biopolymers for Cultured Pearl Production

Type Article
Date 2015-06
Language English
Author(s) Simon-Colin Christelle1, Gueguen YannickORCID2, 3, Bachere Evelyne2, Kouzayha Achraf4, Saulnier Denis3, Gayet Nicolas1, Guezennec Jean5
Affiliation(s) 1 : IFREMER, Ctr Brest, F-29280 Plouzane, France.
2 : Univ Montpellier 2, CNRS, UPVD, Ifremer UMR IHPE 5244, F-34095 Montpellier, France.
3 : UPF ILM IRD, IFREMER, UMR EIO 241, Labex Corail, Taravao 98719, Fr Polynesia.
4 : Lebanese Univ, Sect 3, Dept Biochem, Fac Sci, Tripoli, Lebanon.
5 : AiMB, F-29280 Plouzane, France.
Source Marine Drugs (1660-3397) (Mdpi Ag), 2015-06 , Vol. 13 , N. 6 , P. 3732-3744
DOI 10.3390/md13063732
WOS© Times Cited 13
Note This article belongs to the Special Issue Marine Peptides and Their Mimetics
Keyword(s) pearl oyster, exopolysaccharide, tachyplesin, antimicrobial
Abstract Cultured pearls are the product of grafting and rearing of Pinctada margaritifera pearl oysters in their natural environment. Nucleus rejections and oyster mortality appear to result from bacterial infections or from an inappropriate grafting practice. To reduce the impact of bacterial infections, synthetic antibiotics have been applied during the grafting practice. However, the use of such antibiotics presents a number of problems associated with their incomplete biodegradability, limited efficacy in some cases, and an increased risk of selecting for antimicrobial resistant bacteria. We investigated the application of a marine antimicrobial peptide, tachyplesin, which is present in the Japanese horseshoe crab Tachypleus tridentatus, in combination with two marine bacterial exopolymers as alternative treatment agents. In field studies, the combination treatment resulted in a significant reduction in graft failures vs. untreated controls. The combination of tachyplesin (73 mg/L) with two bacterial exopolysaccharides (0.5% w/w) acting as filming agents, reduces graft-associated bacterial contamination. The survival data were similar to that reported for antibiotic treatments. These data suggest that non-antibiotic treatments of pearl oysters may provide an effective means of improving oyster survival following grafting procedures.
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Simon-Colin Christelle, Gueguen Yannick, Bachere Evelyne, Kouzayha Achraf, Saulnier Denis, Gayet Nicolas, Guezennec Jean (2015). Use of Natural Antimicrobial Peptides and Bacterial Biopolymers for Cultured Pearl Production. Marine Drugs, 13(6), 3732-3744. Publisher's official version : , Open Access version :