FN Archimer Export Format
PT J
TI β-N-methylamino-l-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea
BT 
AF REVEILLON, Damien
   ABADIE, Eric
   SECHET, Veronique
   MASSERET, Estelle
   HESS, Philipp
   AMZIL, Zouher
AS 1:1;2:2;3:1;4:3;5:1;6:1;
FF 1:PDG-ODE-LITTORAL-PHYC;2:PDG-ODE-LITTORAL-LERLR;3:PDG-ODE-LITTORAL-PHYC;4:;5:PDG-ODE-LITTORAL-PHYC;6:PDG-ODE-LITTORAL-PHYC;
C1 IFREMER, Lab Phycotoxines, F-44311 Nantes, France.
   Univ Montpellier, IFREMER, UMR MARBEC, Lab Environm Ressources Languedoc Roussillon,IRD, Sete 3, France.
   Univ Montpellier, IFREMER, CNRS, UMR MARBEC,IRD, F-34095 Montpellier 5, France.
C2 IFREMER, FRANCE
   UNIV MONTPELLIER, FRANCE
   UNIV MONTPELLIER, FRANCE
SI NANTES
   SETE
SE PDG-ODE-LITTORAL-PHYC
   PDG-ODE-LITTORAL-LERLR
UM MARBEC
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 2.769
TC 68
UR https://archimer.ifremer.fr/doc/00275/38607/37192.pdf
LA English
DT Article
DE ;BMAA;Diatoms;Chaetoceros sp.;Seston;Mytilus galloprovincialis;HILIC-MS/MS
AB The neurotoxin BMAA (β-N-methylamino-l-alanine) and its isomer DAB (2,4-diaminobutyric acid) have been detected in seafood worldwide, including in Thau lagoon (French Mediterranean Sea). A cluster of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease associated with BMAA, has also been observed in this region. Mussels, periphyton (i.e. biofilms attached to mussels) and plankton were sampled between July 2013 and October 2014, and analyzed using HILIC-MS/MS. BMAA, DAB and AEG (N-(2-aminoethyl)glycine) were found in almost all the samples of the lagoon. BMAA and DAB were present at 0.58 and 0.83, 2.6 and 3.3, 4.0 and 7.2 μg g−1 dry weight in plankton collected with nets, periphyton and mussels, respectively. Synechococcus sp., Ostreococcus tauri, Alexandrium catenella and eight species of diatoms were cultured and screened for BMAA and analogs. While Synechococcus sp., O. tauri and A. catenella did not produce BMAA under our culture conditions, four diatoms species contained both BMAA and DAB. Hence, diatoms may be a source of BMAA for mussels. Unlike other toxins produced by microalgae, BMAA and DAB were detected in significant amounts in tissues other than digestive glands in mussels.
PY 2015
PD SEP
SO Marine Environmental Research
SN 0141-1136
PU Elsevier Sci Ltd
VL 110
UT 000362304700002
BP 8
EP 18
DI 10.1016/j.marenvres.2015.07.015
ID 38607
ER

EF