FN Archimer Export Format
PT J
TI Antiviral immunity in marine molluscs
BT 
AF GREEN, Timothy J.
   RAFTOS, David
   SPECK, Peter
   MONTAGNANI, Caroline
AS 1:1,2;2:1,2;3:3;4:4;
FF 1:;2:;3:;4:PDG-RBE-IHPE;
C1 Macquarie Univ, Dept Biol Sci, N Ryde, NSW 2109, Australia.
   Sydney Inst Marine Sci, Mosman, NSW 2088, Australia.
   Flinders Univ S Australia, Sch Biol Sci, Adelaide, SA 5001, Australia.
   Univ Montpellier, CNRS, UMR 5244, IFREMER,IHPE,Univ Perpignan, F-34095 Montpellier, France.
C2 UNIV MACQUARIE, AUSTRALIA
   SYDNEY INST MARINE SCI, AUSTRALIA
   UNIV S AUSTRALIA FLINDERS, AUSTRALIA
   IFREMER, FRANCE
SI MONTPELLIER
SE PDG-RBE-IHPE
UM IHPE
IN WOS Ifremer jusqu'en 2018
   copubli-int-hors-europe
IF 3.192
TC 54
UR https://archimer.ifremer.fr/doc/00296/40743/39736.pdf
LA English
DT Article
AB Marine molluscs, like all living organisms, are constantly exposed to viruses and have evolved efficient antiviral defences. We review here recent developments in molluscan antiviral immunity against viruses belonging to the order Herpesvirales. Emerging results suggest an interferon-like response and autophagy are involved in the antiviral defence of bivalves to viral infection. Multifunctional plasma proteins from gastropods and bivalves have been identified to have broadspectrum antiviral activity against mammalian viruses. The antiviral defences present in molluscs can be enhanced by genetic selection, as shown by the presence of oyster strains specifically resistant to ostreid herpesvirus type 1. Whether varying amounts or different isofornns of these antiviral plasma proteins contributes to genetic resistance is worthy of further research. Other evolutionarily conserved antiviral mechanisms, such as RNA interference and apoptosis, still need further characterization.
PY 2015
PD SEP
SO Journal Of General Virology
SN 0022-1317
PU Soc General Microbiology
VL 96
UT 000363915400001
BP 2471
EP 2482
DI 10.1099/jgv.0.000244
ID 40743
ER

EF