FN Archimer Export Format
PT J
TI Effects of an environmentally relevant concentration of diuron on oyster genitors during gametogenesis: responses of early molecular and cellular markers and physiological impacts
BT 
AF AKCHA, Farida
   BARRANGER, Audrey
   BACHERE, Evelyne
   BERTHELIN, C. Heude
   PIQUEMAL, D.
   ALONSO, P.
   SALLAN, R. Rondon
   DIMASTROGIOVANNI, G.
   PORTE, C.
   MENARD, Dominique
   SZCZYBELSKI, A.
   BENABDELMOUNA, Abdellah
   AUFFRET, M.
   ROUXEL, Julien
   BURGEOT, Thierry
AS 1:1;2:1;3:2;4:3;5:4;6:2;7:2;8:5;9:5;10:1;11:1;12:6;13:7;14:1;15:1;
FF 1:PDG-RBE-BE-LBEX;2:PDG-RBE-BE-LBEX;3:PDG-RBE-IHPE;4:;5:;6:;7:;8:;9:;10:PDG-RBE-BE-LBEX;11:;12:PDG-RBE-SG2M-LGPMM;13:;14:PDG-RBE-BE-LBEX;15:PDG-RBE-BE;
C1 IFREMER, Lab Ecotoxicol, Rue Ile Yeu,BP21105, F-44311 Nantes 03, France.
   Univ Montpellier, Interact Host Pathogen Environm, UMR 5244, Ifremer,UPVD,CNRS, CC 80, F-34095 Montpellier, France.
   Univ Paris 06, Univ Paris 04, Unite Biol Organismes & Ecosyst Aquat BOREA,CNRS, Univ Caen Normandie,Museum Natl Hist Nat,UMR 7208, 57 Rue Cuvier, F-75005 Paris, France.
   Acobiom, Cap Delta Biopole Euromed 2, 1682 Rue Valsiere,CS 77394, F-34184 Montpellier 04, France.
   IDAEA CSIC, Dept Environm Chem, Barcelona 1808034, Spain.
   IFREMER, Lab Genet & Pathol, Rue Mus Loup, F-17390 La Tremblade, France.
   UBO CNRS IRD IFREMER, Inst Univ Europeen Mer, Lab Sci Environm Marin LEMAR, Rue Dumont Urville, F-29280 Plouzane, France.
C2 IFREMER, FRANCE
   UNIV MONTPELLIER, FRANCE
   MNHN, FRANCE
   ACOBIOM, FRANCE
   IDAEA CSIC, SPAIN
   IFREMER, FRANCE
   UBO, FRANCE
SI NANTES
   MONTPELLIER
   LA TREMBLADE
SE PDG-RBE-BE-LBEX
   PDG-RBE-IHPE
   PDG-RBE-SG2M-LGPMM
   PDG-RBE-BE
UM LEMAR
   IHPE
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-europe
   copubli-univ-france
IF 2.741
TC 24
UR https://archimer.ifremer.fr/doc/00309/41983/83232.pdf
LA English
DT Article
DE ;Oyster;Pesticide;Reproduction;Histology;Gene expression;RT-qPCR;Steroid;Immunity
AB Genitors of the Pacific oyster Crassostrea gigas were submitted during gametogenesis to a short pulse exposure to the herbicide diuron at a realistic environmental concentration. Histological analysis showed no effect of diuron on gametogenesis course, sex ratio and reproductive effort. A non-significant increase in testosterone and progesterone levels was observed in genitors exposed to the herbicide. At cell level, diuron exposure was shown to modulate the phagocytic activity of circulating hemocytes. The results of a transcriptional analysis showed that diuron affected the expression of genes belonging to functions known to play a major role during oyster gametogenesis such as gene transcription regulation, DNA replication and repair, DNA methylation and cytokinesis. Taking into account the results we previously obtained on the same genitors, this study showed a negative effect of diuron on oyster reproduction by inducing both structural and functional modifications of the DNA.
PY 2016
PD APR
SO Environmental Science And Pollution Research
SN 0944-1344
PU Springer Heidelberg
VL 23
IS 8
UT 000374994600091
BP 8008
EP 8020
DI 10.1007/s11356-015-5969-2
ID 41983
ER

EF