FN Archimer Export Format
PT J
TI Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios
BT 
AF ABI-KHALIL, Celina
   LOPEZ-JOVEN, Carmen
   ABADIE, Eric
   SAVAR, Veronique
   AMZIL, Zouher
   LAABIR, Mohamed
   ROLLAND, Jean-Luc
AS 1:1;2:1;3:2;4:3;5:3;6:2;7:1;
FF 1:;2:;3:PDG-ODE-LITTORAL-LERLR;4:PDG-ODE-DYNECO-PHYC;5:PDG-ODE-DYNECO-PHYC;6:;7:PDG-RBE-IHPE;
C1 Univ Montpellier, Univ Perpignan Via Domitia, Inst Francais Rech Exploitat Mer IFREMER,CNRS, Interact Hotes Pathogenes Environm IHPE UMR 5244, F-34095 Montpellier, France.
   Univ Montpellier, CNRS,IRD, Ctr MARine Biodivers Exploitat & Conservat MARBEC, Inst Francais Rech Exploitat Mer IFREMER,UMR 9190, F-34095 Montpellier, France.
   Inst Francais Rech Exploitat Mer IFREMER, Phycotoxines Lab, Iled Yeu St BP 21105, F-44311 Nantes 3, France.
C2 UNIV MONTPELLIER, FRANCE
   UNIV MONTPELLIER, FRANCE
   IFREMER, FRANCE
SI SETE
   NANTES
   MONTPELLIER
SE PDG-ODE-LITTORAL-LERLR
   PDG-ODE-DYNECO-PHYC
   PDG-RBE-IHPE
UM MARBEC
   IHPE
IN WOS Ifremer jusqu'en 2018
   DOAJ
   copubli-france
   copubli-univ-france
IF 3.03
TC 14
UR https://archimer.ifremer.fr/doc/00309/42016/41308.pdf
   https://archimer.ifremer.fr/doc/00309/42016/41309.pdf
LA English
DT Article
DE ;harmful algae;environment;interaction;pathogens;defense;paralytic shellfish toxin
AB The multifactorial etiology of massive Crassostrea gigas summer mortalities results from complex interactions between oysters, opportunistic pathogens and environmental factors. In a field survey conducted in 2014 in the Mediterranean Thau Lagoon (France), we evidenced that the development of the toxic dinoflagellate Alexandrium catenella, which produces paralytic shellfish toxins (PSTs), was concomitant with the accumulation of PSTs in oyster flesh and the occurrence of C. gigas mortalities. In order to investigate the possible role of toxic algae in this complex disease, we experimentally infected C. gigas oyster juveniles with Vibrio tasmaniensis strain LGP32, a strain associated with oyster summer mortalities, after oysters were exposed to Alexandrium catenella. Exposure of oysters to A. catenella significantly increased the susceptibility of oysters to V. tasmaniensis LGP32. On the contrary, exposure to the non-toxic dinoflagellate Alexandrium tamarense or to the haptophyte Tisochrysis lutea used as a foraging alga did not increase susceptibility to V. tasmaniensis LGP32. This study shows for the first time that A. catenella increases the susceptibility of Crassostrea gigas to pathogenic vibrios. Therefore, in addition to complex environmental factors explaining the mass mortalities of bivalve mollusks, feeding on neurotoxic dinoflagellates should now be considered as an environmental factor that potentially increases the severity of oyster mortality events.
PY 2016
PD JAN
SO Toxins
SN 2072-6651
PU Mdpi Ag
VL 8
IS 24
UT 000374332700024
BP 1
EP 14
DI 10.3390/toxins8010024
ID 42016
ER

EF