FN Archimer Export Format PT J TI Complementary approaches to diagnosing marine diseases: a union of the modern and the classic BT AF BURGE, Colleen A. FRIEDMAN, Carolyn S. GETCHELL, Rodman HOUSE, Marcia LAFFERTY, Kevin D. MYDLARZ, Laura D. PRAGER, Katherine C. SUTHERLAND, Kathryn P. RENAULT, Tristan KIRYU, Ikunari VEGA-THURBER, Rebecca AS 1:1;2:2;3:3;4:4;5:5;6:6;7:7,8;8:9;9:10;10:11;11:12; FF 1:;2:;3:;4:;5:;6:;7:;8:;9:PDG-RBE-SG2M-LGPMM;10:;11:; C1 Univ Maryland Baltimore Cty, Inst Marine & Environm Technol, 701 E Pratt St, Baltimore, MD 21202 USA. Univ Washington, Sch Aquat & Fishery Sci, Box 355020, Seattle, WA 98195 USA. Cornell Univ, Coll Vet Med, Dept Microbiol & Immunol, Vet Med Ctr C4 177, 930 Campus Rd, Ithaca, NY 14853 USA. Northwest Indian Fisheries Commiss, 6730 Martin Way East, Olympia, WA 98516 USA. Univ Calif Santa Barbara, Inst Marine Sci, Western Ecol Res Ctr, US Geol Survey, Santa Barbara, CA 93106 USA. Univ Texas Arlington, Dept Biol, 501 South Nedderman, Arlington, TX 76019 USA. Univ Calif Los Angeles, Dept Ecol & Evolutionary Biol, Los Angeles, CA 90095 USA. NIH, Fogarty Int Ctr, Bldg 10, Bethesda, MD 20892 USA. Rollins Coll, Dept Biol, Winter Pk, FL 32789 USA. IFREMER, Dept Ressources Biol & Environm, Rue Ile Yeu, F-44311 Nantes 03, France. Fisheries Res Agcy, Natl Res Inst Aquaculture, Tsu, Mie 5160193, Japan. Oregon State Univ, 454 Nash Hall, Corvallis, OR 97330 USA. C2 UNIV MARYLAND BALTIMORE CTY, USA UNIV WASHINGTON, USA UNIV CORNELL, USA NORTHWEST INDIAN FISHERIES COMMISS, USA UNIV CALIF SANTA BARBARA, USA UNIV TEXAS ARLINGTON, USA UNIV CALIF LOS ANGELES, USA NIH, USA ROLLINS COLL, USA IFREMER, FRANCE FISHERIES RES AGCY, JAPAN UNIV OREGON STATE, USA SI NANTES SE PDG-RBE-SG2M-LGPMM IN WOS Ifremer jusqu'en 2018 copubli-int-hors-europe IF 5.846 TC 43 UR https://archimer.ifremer.fr/doc/00314/42536/41911.pdf https://archimer.ifremer.fr/doc/00314/42536/41913.pdf https://archimer.ifremer.fr/doc/00314/42536/41914.pptx LA English DT Article DE ;marine disease;aetiology;diagnostics;marine epizootics AB Linking marine epizootics to a specific etiology is notoriously difficult. Recent diagnostic successes show that marine disease diagnosis requires both modern, cutting-edge technology (e.g. metagenomics, quantitative realtime PCR) and more classic methods (e.g. transect surveys, histopathology and cell culture). Here, we discuss how this combination of traditional and modern approaches is necessary for rapid and accurate identification of marine diseases, and emphasize how sole reliance on any one technology or technique may lead disease investigations astray. We present diagnostic approaches at different scales, from the macro (environment, community, population and organismal scales) to the micro (tissue, organ, cell and genomic scales). We use disease case studies from a broad range of taxa to illustrate diagnostic successes from combining traditional and modern diagnostic methods. Finally, we recognize the need for increased capacity of centralized databases, networks, data repositories and contingency plans for diagnosis and management of marine disease. PY 2016 PD MAR SO Philosophical Transactions Of The Royal Society B-biological Sciences SN 0962-8436 PU Royal Soc VL 371 IS 1689 UT 000371148300005 BP 1 EP 11 DI 10.1098/rstb.2015.0207 ID 42536 ER EF