TY - JOUR T1 - PAH metabolites in fish bile: from the Seine Estuary to Iceland A1 - Kammann,U. A1 - Akcha,Farida A1 - Budzinski,H. A1 - Burgeot,Thierry A1 - Gubbins,M. J. A1 - Lang,T. A1 - Le Menach,K. A1 - Vethaak,A. D. A1 - Hylland,K. AD - Thunen Inst Fisheries Ecol, Palmaille 9, D-22767 Hamburg, Germany. AD - IFREMER, Dept Biogeochem & Ecotoxicol, BP 21105, F-44311 Nantes 03, France. AD - Univ Bordeaux 1, CNRS, ISM, Lab Phys & Toxicochem Environm LPTC,UMR 5255, BP 21105, F-33405 Talence, France. AD - Vrije Univ Amsterdam, Inst Environm Studies IVM, Boelelaan 1087, NL-1081 HV Amsterdam, Netherlands. AD - FRS Marine Lab, 375 Victoria Rd, Aberdeen AB11 9DB, Scotland. AD - Univ Oslo, Dept Biol, Pb 1066, N-0316 Oslo, Norway. AD - Norwegian Inst Water Res NIVA, Gaustadalleen 21, N-0349 Oslo, Norway. UR - https://doi.org/10.1016/j.marenvres.2016.02.014 DO - 10.1016/j.marenvres.2016.02.014 KW - PAH metabolite KW - Dab KW - Flounder KW - Haddock KW - Marine monitoring KW - Atlantic KW - North Sea N2 - Polycyclic aromatic hydrocarbons (PAH) are environmental contaminants that pose significant risk to health of fish. The International Workshop on Integrated Assessment of Contaminant Impacts on the North Sea (ICON) provided the framework to investigate biomarker responses as well as contaminant concentrations side by side in marine ecosystems. Concentrations of the main PAH metabolites 1-hydroxypyrene, 1-hydroxyphenanthren and 3-hydroxybenzo(a)pyrene were determined in bile by HPLC with fluorescence detection. Fish species under investigation were dab (Limanda limanda), flounder (Platichthys flesus) and haddock (Melanogrammus aeglefinus). A contamination gradient was demonstrated from the low contaminated waters of Iceland and off-shore regions of the North Sea towards higher concentrations in coastal areas. Concentrations of PAH metabolites differed primarily according to sampling region and secondarily to species. Y1 - 2017/03 PB - Elsevier Sci Ltd JF - Marine Environmental Research SN - 0141-1136 VL - 124 SP - 41 EP - 45 ID - 42861 ER -