FN Archimer Export Format
PT J
TI Enzyme-assisted extraction (EAE) for the production of antiviral and antioxidant extracts from the green seaweed Ulva armoricana (Ulvales, Ulvophyceae)
BT 
AF HARDOUIN, Kevin
   BEDOUX, Gilles
   BURLOT, Anne-Sophie
   DONNAY-MORENO, Claire
   BERGE, Jean-Pascal
   NYVALL-COLLEN, Pi
   BOURGOUGNON, Nathalie
AS 1:1,2;2:1;3:1;4:4;5:;6:3,5;7:1;
FF 1:;2:;3:;4:PDG-RBE-BRM-LEMMMB;5:;6:;7:;
C1 Univ Bretagne Sud, LBCM, IUEM, EA 3884, F-56000 Vannes, France.
   SA OLMIX, ZA Haut Bois, F-56580 Brehan, France.
   Amadeite SAS, Pole Biotechnol Haut Bois, F-56580 Brehan, France.
   IFREMER, Lab BIORAFhe, Rue Ile Yeu,BP 21105, F-44311 Nantes 03, France.
   IDMer, 2 Rue Bateliere, F-56100 Lorient, France.
C2 UBS, FRANCE
   SA OLMIX, FRANCE
   AMADEITE SAS, FRANCE
   IFREMER, FRANCE
   IDMER, FRANCE
SI NANTES
SE PDG-RBE-BRM-LEMMMB
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 3.994
TC 104
UR https://archimer.ifremer.fr/doc/00321/43187/45542.pdf
LA English
DT Article
DE ;Ulvan;Antiviral activity;Carbohydrate;Endo-protease;Bioconversion;Biorefinery
AB In order to develop innovative methods for the production of bioactive extracts with potential health benefits, enzyme-assisted extraction has been applied for the bioconversion of Ulva armoricana (Ulvales, Ulvophyceae). The extraction yields, chemical composition, the antioxidant and antiviral activities were determined to assess the efficiency of six commercial enzymatic preparations. Endo-protease treatments significantly increased the extraction yields compared to the control. The organic matter, neutral sugar and protein contents were increased in all extracts compared to an extraction with water, up to 2.0-fold, 2.7-fold and 1.75-fold, respectively. The samples prepared by a multiple-mix of glycosyl-hydrolases and an exo-β-1,3(4)-glucanase revealed activities against herpes simplex virus type-1 at the median effective concentration (EC50) of 373.0 ± 20.7 and 320.9 ± 33.6 μg/ml, respectively. These activities were correlated to high amounts of rhamnose, uronic acids and sulfate groups which are the main constituents of ulvans. Free radical scavenging capacity at medium inhibition concentrations (IC50) of 1.8 and 12.5 mg/ml was shown for the extracts produced with endo-protease treatments and 6.0 mg/ml for the sample resulting from the extraction with the multiple-mix of glycosyl-hydrolases. This study reports the antiviral and antioxidant activities of Ulva armoricana extracts produced by enzyme-assisted extraction.
PY 2016
PD JUL
SO Algal Research-biomass Biofuels And Bioproducts
SN 2211-9264
PU Elsevier Science Bv
VL 16
UT 000375610000027
BP 233
EP 239
DI 10.1016/j.algal.2016.03.013
ID 43187
ER

EF