FN Archimer Export Format PT J TI Oysters and Vibrios as a Model for Disease Dynamics in Wild Animals BT AF LE ROUX, Frederique WEGNER, K. Mathias POLZ, Martin F. AS 1:1,2;2:3;3:4; FF 1:PDG-RBE-PFOM;2:;3:; C1 IFREMER, Unite Physiol Fonct Organismes Marins, ZI Pointe Diable, CS 10070, F-29280 Plouzane, France. Univ Paris 06, Univ Paris 04, CNRS, UMR 8227,Integrat Biol Marine Models,Stn Biol Ros, CS 90074, F-29688 Roscoff, France. Helmholtz Zentrum Polar & Meeresforsch, AWI, Coastal Ecol, Waddensea Stn Sylt, Hafenstr 43, D-25992 List Auf Sylt, Germany. MIT, Parsons Lab Environm Sci & Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA. C2 IFREMER, FRANCE UNIV PARIS 06, FRANCE HELMHOLTZ ZENTRUM, GERMANY MIT, USA SI ROSCOFF SE PDG-RBE-PFOM IN WOS Ifremer jusqu'en 2018 copubli-france copubli-europe copubli-univ-france copubli-int-hors-europe IF 11.02 TC 94 UR https://archimer.ifremer.fr/doc/00323/43466/46569.pdf LA English DT Article AB Disease dynamics in the wild are influenced by a number of ecological and evolutionary factors not addressed by traditional laboratory-based characterization of pathogens. Here we propose the oyster, Crassostrea gigas, as a model for studying the interaction of the environment, bacterial pathogens, and the host in disease dynamics. We show that an important first step is to ask whether the functional unit of pathogenesis is a bacterial clone, a population, or a consortium in order to assess triggers of disease outbreaks and devise appropriate monitoring tools. Moreover, the development of specific-pathogen-free (SPF) oysters has enabled assessment of the infection process under natural conditions. Finally, recent results show the importance of microbial interactions and host genetics in determining oyster health and disease. PY 2016 PD JUN SO Trends In Microbiology SN 0966-842X PU Elsevier Sci Ltd VL 24 IS 7 UT 000379100300010 BP 568 EP 580 DI 10.1016/j.tim.2016.03.006 ID 43466 ER EF