FN Archimer Export Format PT J TI Detection of Hepatitis E Virus in Sewage After an Outbreak on a French Island BT AF MIURA, Takayuki LHOMME, Sebastien LE SAUX, Jean-Claude LE MEHAUTE, Philippe GUILLOIS, Yvonnick COUTURIER, Elizabeth IZOPET, Jacques ABRANAVEL, Florence LE GUYADER, Soizick AS 1:1,6;2:2;3:1;4:3;5:4;6:5;7:2;8:2;9:1; FF 1:;2:;3:PDG-RBE-SG2M-LSEM;4:;5:;6:;7:;8:;9:PDG-RBE-SG2M-LSEM; C1 IFREMER, Lab Microbiol, LSEM SG2M, BP 21105, F-44311 Nantes 03, France. Ctr Hosp Univ, Natl Reference Ctr HEV, Toulouse, France. SAUR, Direct Gen Ouest, Vannes, France. Inst Veille Sanit, Reg Epidemiol Unit Brittany Reg, Rennes, France. Inst Veille Sanit, Dept Infect Dis, St Maurice, France. Tohoku Univ, New Ind Creat Hatchery Ctr NICHe, Aoba Ku, 6-6-04 Aoba, Sendai, Miyagi 9808579, Japan. C2 IFREMER, FRANCE CHU TOULOUSE, FRANCE SAUR, FRANCE INVS, FRANCE INVS, FRANCE UNIV TOHOKU, JAPAN SI BREST NANTES SE PDG-RBE-SG2M-LSEM IN WOS Ifremer jusqu'en 2018 copubli-france copubli-int-hors-europe IF 1.847 TC 40 UR https://archimer.ifremer.fr/doc/00334/44482/44199.pdf LA English DT Article DE ;Hepatitis E virus;Wastewater treatment plant;Quantification AB A hepatitis E outbreak, which occurred on a small isolated island, provided an opportunity to evaluate the association between the number of hepatitis E cases in the community and the concentration of virus detected in sewage. Samples were collected from the different sewage treatment plants from the island and analyzed for the presence of hepatitis E (HEV) virus using real-time RT-PCR. We demonstrated that if 1–4 % of inhabitants connected to a WWTP were infected with HEV, raw sewage contained HEV at detectable levels. The finding that such a small number of infected people can contaminate municipal sewage works raises the potential of the further distribution of the virus. Indeed, investigating the routes of transmission of HEV, including the potential for sewage effluent to contain infectious HEV, may help us to better understand the epidemiology of this pathogen, which is considered to be an emerging concern in Europe PY 2016 PD SEP SO Food And Environmental Virology SN 1867-0334 PU Springer VL 8 IS 3 UT 000381161000005 BP 194 EP 199 DI 10.1007/s12560-016-9241-9 ID 44482 ER EF