FN Archimer Export Format
PT J
TI Ionic composition of endolymph in teleosts: Origin and importance of endolymph alkalinity
BT 
AF PAYAN, P
   KOSSMANN, Hans
   WATRIN, A
   MAYER-GOSTAN, N
   BOEUF, Gilles
AS 1:1;2:2;3:3;4:3;5:2;
FF 1:;2:;3:;4:;5:;
C1 UNIV NICE,FAC SCI,ENVIRONM PHYSIOL LAB,BP 71,F-06108 NICE CX2,FRANCE.
   IFREMER,CTR BREST,PHYSIOL POISSONS LAB,F-29280 PLOUZANE,FRANCE.
   UNIV NICE,FAC SCI,URA CNRS 1938,LAB PHYSIOL CELLULAIRE & MOL EPITHELIUMS & COMPAR,F-06108 NICE CX2,FRANCE.
C2 UNIV NICE, FRANCE
   IFREMER, FRANCE
   UNIV NICE, FRANCE
IN WOS Ifremer jusqu'en 2018
IF 1.989
TC 84
UR https://archimer.ifremer.fr/doc/00336/44695/44987.pdf
LA English
DT Article
DE ;teleost;inner ear;saccular epithelium;proton secretion;otolith;biocalcification;trout;Oncorhynchus mykiss;turbot;Scophthalmus maximus
AB Ionic (Na+, K+, Cl-, PO43-, pH), total CO2, total calcium and protein concentrations in the plasma and endolymph of the inner ear were compared in trout Oncorhynchus mykiss and turbot Scophthalmus maximus. In both species, saccular endolymph was characterized by high levels of K+ and total CO2 and in trout by an alkaline pH, The kinetic characteristics of proton secretion across the saccular epithelium of trout were investigated using a titration technique in which isolated saccules were mounted as closed sacs. The rate of proton secretion depends strongly on the pH of the Ringer's solution and secretion stops at a pH below 7.2, Proton secretion is driven by an energy-dependent mechanism involving basolateral ouabain-sensitive Na+/K+ exchangers. Proton secretion was partially inhibited by acetazolamide and completely inhibited in Na+-free Ringer or in the presence of 1 mmol l(-1) amiloride. A cellular model stressing the importance of proton exchange through the saccular epithelium is proposed to explain the regulation of endolymph pH, a crucial factor for the deposition of otolith calcium.
PY 1997
PD JUN
SO Journal Of Experimental Biology
SN 0022-0949
PU Company Of Biologists Ltd
VL 200
IS 13
UT A1997XK16200008
BP 1905
EP 1912
ID 44695
ER

EF