TY - JOUR T1 - Antimicrobial peptides in marine invertebrate health and disease A1 - Destoumieux-Garzon,Delphine A1 - Rosa,Rafael Diego A1 - Schmitt,Paulina A1 - Barreto,Caire A1 - Vidal-Dupiol,Jeremie A1 - Mitta,Guillaume A1 - Gueguen,Yannick A1 - Bachere,Evelyne AD - CNRS, Pl Eugene Bataillon, F-34090 Montpellier, France. AD - IFREMER, Pl Eugene Bataillon, F-34090 Montpellier, France. AD - UPVD, Pl Eugene Bataillon, F-34090 Montpellier, France. AD - Univ Montpellier, IHPE, UMR5244, Pl Eugene Bataillon, F-34090 Montpellier, France. AD - Univ Fed Santa Catarina, Dept Cell Biol Embryol & Genet, Lab Immunol Appl Aquaculture, BR-88040900 Florianopolis, SC, Brazil. AD - Pontificia Univ Catolica Valparaiso, Inst Biol, Lab Genet & Inmunol Mol, Ave Univ 330, Valparaiso 2373223, Chile. AD - IFREMER, LabexCorail, UMR EIO 241, BP 7004, Taravao 98719, Tahiti, Fr Polynesia. UR - https://archimer.ifremer.fr/doc/00341/45220/ DO - 10.1098/rstb.2015.0300 KW - invertebrate immunity KW - polymicrobial disease KW - vibrio KW - immune suppression KW - resistance KW - abiotic stress N2 - Aquaculture contributes more than one-third of the animal protein from marine sources worldwide. A significant proportion of aquaculture products are derived from marine protostomes that are commonly referred to as 'marine invertebrates'. Among them, penaeid shrimp (Ecdysozosoa, Arthropoda) and bivalve molluscs (Lophotrochozoa, Mollusca) are economically important. Mass rearing of arthropods and molluscs causes problems with pathogens in aquatic ecosystems that are exploited by humans. Remarkably, species of corals (Cnidaria) living in non-exploited ecosystems also suffer from devastating infectious diseases that display intriguing similarities with those affecting farmed animals. Infectious diseases affecting wild and farmed animals that are present in marine environments are predicted to increase in the future. This paper summarizes the role of the main pathogens and their interaction with host immunity, with a specific focus on antimicrobial peptides (AMPs) and pathogen resistance against AMPs. We provide a detailed review of penaeid shrimp AMPs and their role at the interface between the host and its resident/pathogenic microbiota. We also briefly describe the relevance of marine invertebrate AMPs in an applied context. This article is part of the themed issue 'Evolutionary ecology of arthropod antimicrobial peptides'. Y1 - 2016/05 PB - Royal Soc JF - Philosophical Transactions Of The Royal Society B-biological Sciences SN - 0962-8436 VL - 371 IS - 1695 SP - 1 EP - 11 ID - 45220 ER -