FN Archimer Export Format
PT J
TI Rare sex or out of reach equilibrium? The dynamics of F-IS in partially clonal organisms
BT
AF REICHEL, Katja
MASSON, Jean-Pierre
MALRIEU, Florent
ARNAUD-HAOND, Sophie
STOECKEL, Solenn
AS 1:1;2:1;3:2;4:3;5:1;
FF 1:;2:;3:;4:PDG-RBE-MARBEC-LHM;5:;
C1 Univ Rennes 1, INRA, Agrocampus Ouest, IGEPP, F-35650 Le Rheu, France.
Univ Tours, CNRS, LMPT, UMR7350, F-37200 Tours, France.
IFREMER, UMR5240, MARBEC, F-34203 Sete, France.
C2 UNIV RENNES, FRANCE
UNIV TOURS, FRANCE
IFREMER, FRANCE
SI SETE
SE PDG-RBE-MARBEC-LHM
UM MARBEC
IN WOS Ifremer jusqu'en 2018
copubli-france
copubli-univ-france
IF 2.266
TC 13
UR https://archimer.ifremer.fr/doc/00344/45474/45019.pdf
LA English
DT Article
DE ;Partial asexuality;Parthenogenesis;Mating system;Inbreeding coefficient;Heterozygote excess;Genetic diversity
AB Background: Partially clonal organisms are very common in nature, yet the influence of partial asexuality on the temporal dynamics of genetic diversity remains poorly understood. Mathematical models accounting for clonality predict deviations only for extremely rare sex and only towards mean inbreeding coefficient (F-IS) over bar < 0. Yet in partially clonal species, both F-IS < 0 and F-IS > 0 are frequently observed also in populations where there is evidence for a significant amount of sexual reproduction. Here, we studied the joint effects of partial clonality, mutation and genetic drift with a state-and-time discrete Markov chain model to describe the dynamics of F-IS over time under increasing rates of clonality. Results: Results of the mathematical model and simulations show that partial clonality slows down the asymptotic convergence to F-IS = 0. Thus, although clonality alone does not lead to departures from Hardy-Weinberg expectations once reached the final equilibrium state, both negative and positive F-IS values can arise transiently even at intermediate rates of clonality. More importantly, such "transient" departures from Hardy Weinberg proportions may last long as clonality tunes up the temporal variation of F-IS and reduces its rate of change over time, leading to a hyperbolic increase of the maximal time needed to reach the final mean (F-IS,F-infinity) over bar value expected at equilibrium. Conclusion: Our results argue for a dynamical interpretation of F-IS in clonal populations. Negative values cannot be interpreted as unequivocal evidence for extremely scarce sex but also as intermediate rates of clonality in finite populations. Complementary observations (e.g. frequency distribution of multiloci genotypes, population history) or time series data may help to discriminate between different possible conclusions on the extent of clonality when mean (F-IS) over bar values deviating from zero and/or a large variation of F-IS over loci are observed.
PY 2016
PD JUL
SO Bmc Genetics
SN 1471-2156
PU Biomed Central Ltd
VL 17
IS 76
UT 000377578300002
BP 1
EP 16
DI 10.1186/s12863-016-0388-z
ID 45474
ER
EF