FN Archimer Export Format
PT J
TI Exposure of marine mussels Mytilus spp. to polystyrene microplastics: Toxicity and influence on fluoranthene bioaccumulation
BT 
AF PAUL-PONT, Ika
   LACROIX, Camille
   GONZALEZ FERNANDEZ, Carmen
   HEGARET, Helene
   LAMBERT, Christophe
   LE GOIC, Nelly
   FRERE, Laura
   CASSONE, Anne-Laure
   SUSSARELLU, Rossana
   FABIOUX, Caroline
   GUYOMARCH, Julien
   ALBENTOSA, Marina
   HUVET, Arnaud
   SOUDANT, Philippe
AS 1:1;2:1,2;3:3;4:1;5:1;6:1;7:1;8:1;9:4;10:1;11:2;12:3;13:5;14:1;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:PDG-RBE-BE-LBEX;10:;11:;12:;13:PDG-RBE-PFOM-PI;14:;
C1 IFREMER Inst Univ Europeen Mer, Technopole Brest Iroise, Lab Sci Environm Marin LEMAR, CNRS,UBO,IRD,UMR 6539, Rue Dumont dUrville, F-29280 Plouzane, France.
   CEDRE, 715 Rue Alain Colas, F-29218 Brest 2, France.
   IEO, Ctr Oceanog Murcia, Varadero 1, E-30740 Murcia, Spain.
   IFREMER, Lab Ecotoxicol, Nantes, France.
   IFREMER, Lab Sci Environm Marin LEMAR, UMR 6539, UBO,CNRS,IRD,Ctr Bretagne, CS 10070, F-29280 Plouzane, France.
C2 IFREMER, FRANCE
   CEDRE, FRANCE
   IEO, SPAIN
   IFREMER, FRANCE
   IFREMER, FRANCE
   CNRS, FRANCE
SI NANTES
   BREST
SE PDG-RBE-BE-LBEX
   PDG-RBE-PFOM-PI
UM LEMAR
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-europe
IF 5.099
TC 449
UR https://archimer.ifremer.fr/doc/00344/45502/45848.pdf
LA English
DT Article
DE ;Microplastics;Fluoranthene;Mussel;Depuration;Oxidative system
AB The effects of polystyrene microbeads (micro-PS; mix of 2 and 6 μm; final concentration: 32 μg L−1) alone or in combination with fluoranthene (30 μg L−1) on marine mussels Mytilus spp. were investigated after 7 days of exposure and 7 days of depuration under controlled laboratory conditions. Overall, fluoranthene was mostly associated to algae Chaetoceros muelleri (partition coefficient Log Kp = 4.8) used as a food source for mussels during the experiment. When micro-PS were added in the system, a fraction of FLU transferred from the algae to the microbeads as suggested by the higher partition coefficient of micro-PS (Log Kp = 6.6), which confirmed a high affinity of fluoranthene for polystyrene microparticles. However, this did not lead to a modification of fluoranthene bioaccumulation in exposed individuals, suggesting that micro-PS had a minor role in transferring fluoranthene to mussels tissues in comparison with waterborne and foodborne exposures. After depuration, a higher fluoranthene concentration was detected in mussels exposed to micro-PS and fluoranthene, as compared to mussels exposed to fluoranthene alone. This may be related to direct effect of micro-PS on detoxification mechanisms, as suggested by a down regulation of a P-glycoprotein involved in pollutant excretion, but other factors such as an impairment of the filtration activity or presence of remaining beads in the gut cannot be excluded. Micro-PS alone led to an increase in hemocyte mortality and triggered substantial modulation of cellular oxidative balance: increase in reactive oxygen species production in hemocytes and enhancement of anti-oxidant and glutathione-related enzymes in mussel tissues. Highest histopathological damages and levels of anti-oxidant markers were observed in mussels exposed to micro-PS together with fluoranthene. Overall these results suggest that under the experimental conditions of our study micro-PS led to direct toxic effects at tissue, cellular and molecular levels, and modulated fluoranthene kinetics and toxicity in marine mussels.
PY 2016
PD SEP
SO Environmental Pollution
SN 0269-7491
PU Elsevier Sci Ltd
VL 216
UT 000383930500078
BP 724
EP 737
DI 10.1016/j.envpol.2016.06.039
ID 45502
ER

EF